日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene expression dynamics of human and mouse craniofacial development at the single-cell level

人类和小鼠颅面发育的单细胞水平基因表达动态

Khouri-Farah, Nagham; Manchel, Alexandra; Wentworth Winchester, Emma; Schilder, Brian M; Robinson, Kelsey; Curtis, Sarah W; Skene, Nathan G; Leslie-Clarkson, Elizabeth J; Cotney, Justin

Unraveling the Transcription Factor Code of Odontoblast Differentiation

揭开成牙本质细胞分化的转录因子密码

Lavický, J; Lopez, M Gonzalez; Chochola, V; Kompaníková, P; Rakultsev, V; Raška, J; Winchester, E Wentworth; Tuaima, H; Englmaier, L; Verner, J; Švandová, E; Buchtová, M; Cotney, J; Bryja, V; Bohačiaková, D; Bárta, T; Krivanek, J

Leveraging the genetics of human face shape boosts the discovery of orofacial cleft risk loci

利用人类面部形状的遗传学信息可以促进唇腭裂风险基因位点的发现。

Herrick, Noah; Goovaerts, Seppe; Manchel, Alexandra; Lee, Myoung Keun; Zhang, Xinyi; Davies, Amy; Carlson, Jenna C; Leslie-Clarkson, Elizabeth J; Lewis, Sarah J; Marazita, Mary L; Cotney, Justin; Claes, Peter; Shaffer, John R; Weinberg, Seth M

PITX2 expression and Neanderthal introgression in HS3ST3A1 contribute to variation in tooth dimensions in modern humans

PITX2表达和尼安德特人基因渗入HS3ST3A1基因导致现代人类牙齿尺寸的变异。

Li, Qing; Faux, Pierre; Wentworth Winchester, Emma; Yang, Guangrui; Chen, Yingjie; Ramírez, Luis Miguel; Fuentes-Guajardo, Macarena; Poloni, Lauriane; Steimetz, Emilie; Gonzalez-José, Rolando; Acuña, Victor; Bortolini, Maria-Cátira; Poletti, Giovanni; Gallo, Carla; Rothhammer, Francisco; Rojas, Winston; Zheng, Youyi; Cox, James C; Patel, Vaishali; Hoffman, Matthew P; Ding, Li; Peng, Chenchen; Cotney, Justin; Navarro, Nicolas; Cox, Timothy C; Delgado, Miguel; Adhikari, Kaustubh; Ruiz-Linares, Andrés

Functional Annotation of De Novo Variants Found Near GWAS Loci Associated With Cleft Lip With or Without Cleft Palate

对与唇裂(伴或不伴腭裂)相关的 GWAS 位点附近发现的新生变异进行功能注释

Curtis, Sarah W; Cook, Laura E; Paraiso, Kitt; Visel, Axel; Cotney, Justin L; Murray, Jeffrey C; Beaty, Terri H; Marazita, Mary L; Carlson, Jenna C; Leslie-Clarkson, Elizabeth J

Gene expression patterns of the developing human face at single cell resolution reveal cell type contributions to normal facial variation and disease risk

单细胞分辨率下发育中人脸的基因表达模式揭示了不同细胞类型对正常面部变异和疾病风险的贡献。

Khouri-Farah, Nagham; Winchester, Emma Wentworth; Schilder, Brian M; Robinson, Kelsey; Curtis, Sarah W; Skene, Nathan G; Leslie-Clarkson, Elizabeth J; Cotney, Justin

Ube3a unsilencer for the potential treatment of Angelman syndrome

Ube3a 解除沉默剂有望治疗 Angelman 综合征

Hanna Vihma, Kelin Li #, Anna Welton-Arndt #, Audrey L Smith, Kiran R Bettadapur, Rachel B Gilmore, Eric Gao, Justin L Cotney, Hsueh-Cheng Huang, Jon L Collins, Stormy J Chamberlain, Hyeong-Min Lee, Jeffrey Aubé, Benjamin D Philpot

A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development

在小鼠和人类颅面发育过程中,远端全局控制区对于前部 HOXA 基因的正常表达至关重要。

Andrea Wilderman ,Eva D'haene ,Machteld Baetens ,Tara N Yankee ,Emma Wentworth Winchester ,Nicole Glidden ,Ellen Roets ,Jo Van Dorpe ,Sandra Janssens ,Danny E Miller ,Miranda Galey ,Kari M Brown ,Rolf W Stottmann ,Sarah Vergult ,K Nicole Weaver ,Samantha A Brugmann ,Timothy C Cox ,Justin Cotney

Enhanced osteogenic potential of iPSC-derived mesenchymal progenitor cells following genome editing of GWAS variants in the RUNX1 gene

对 RUNX1 基因中的 GWAS 变体进行基因组编辑后,iPSC 衍生的间充质祖细胞的成骨潜能增强

Nazir M Khan, Andrea Wilderman, Jarred M Kaiser, Archana Kamalakar, Steven L Goudy, Justin Cotney, Hicham Drissi

Identifying key underlying regulatory networks and predicting targets of orphan C/D box SNORD116 snoRNAs in Prader-Willi syndrome

识别普拉德-威利综合征中孤儿C/D盒SNORD116 snoRNA的关键潜在调控网络并预测其靶点

Gilmore, Rachel B; Liu, Yaling; Stoddard, Christopher E; Chung, Michael S; Carmichael, Gordon G; Cotney, Justin