日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease.

验证用于 CRISPR-Cas9 介导的基因治疗在原代肝细胞中治疗遗传性代谢性肝病的临床级电穿孔系统

Gibson Justin, Dhungana Abishek, Pokhrel Menam, Arthur Benjamin, Suresh Pramita, Adebayo Olumide, Cottle Renee N

One Shock, Not One Cure: Electroporation Reveals Disease-Specific Constraints in Hepatocyte Gene Editing Therapy.

一次电击,而非一次治愈:电穿孔揭示肝细胞基因编辑疗法中疾病特异性限制

Clark Callie, Pokhrel Menam, Arthur Benjamin, Suresh Pramita, Ates Ilayda, Gibson Justin, Dhungana Abishek, Mehlem Ryan, Boysia Andrew, Padalkar Mugdha V, Pokhrel Achala, Echesabal-Chen Jing, Vonada Anne, Stamatikos Alexis, Savinova Olga V, Grompe Markus, Cottle Renee N

Ex vivo gene editing and cell therapy for hereditary tyrosinemia type 1

体外基因编辑和细胞疗法治疗1型遗传性酪氨酸血症

Ates, Ilayda; Stuart, Callie; Rathbone, Tanner; Barzi, Mercedes; He, Gordon; Major, Angela M; Shankar, Vijay; Lyman, Rachel A; Angner, Sidney S; Mackay, Trudy F C; Srinivasan, Shanthi; Farris, Alton Brad; Bissig, Karl-Dimiter; Cottle, Renee N

In vitro Studies of Transendothelial Migration for Biological and Drug Discovery

体外跨内皮迁移研究及其在生物学和药物发现中的应用

Salminen, Alec T; Allahyari, Zahra; Gholizadeh, Shayan; McCloskey, Molly C; Ajalik, Raquel; Cottle, Renee N; Gaborski, Thomas R; McGrath, James L

Delivery Approaches for Therapeutic Genome Editing and Challenges

治疗性基因组编辑的递送方法及挑战

Ates, Ilayda; Rathbone, Tanner; Stuart, Callie; Bridges, P Hudson; Cottle, Renee N

Treating hemoglobinopathies using gene-correction approaches: promises and challenges

利用基因矫正方法治疗血红蛋白病:前景与挑战

Cottle, Renee N; Lee, Ciaran M; Bao, Gang