日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anticodon-edited transfer RNAs (ACE-tRNAs) encoded as therapeutic nonviral minimal DNA vectors

反密码子编辑的转移RNA(ACE-tRNA)编码为治疗性非病毒最小DNA载体

Porter, Joseph J; Ko, Wooree; Sorensen, Emily G; Cheung, Zachary; Thrasher, Kari; Couch, Tyler; Gabell, Jeffrey T; Shwe, Victoria; Hyatt, Julia; Licata, Jennasea B; Peterson, Luke K; Dean, David A; Lueck, John D

ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosis.

ACE-tRNA 是一种用于抑制导致囊性纤维化的无义突变的平台技术

Ko Wooree, Porter Joseph J, Spelier Sacha, Sorensen Emily G, Bhatt Priyanka, Gabell Jeffrey T, van der Windt Isabelle, Couch Tyler, Coote Kevin, Mense Martin, Beekman Jeffrey M, Lueck John D

The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking

亚基类型、选择性剪接和辅助蛋白对AMPA受体转运的影响

Couch, Tyler; McCullock, Tyler W; MacLean, David M

Metabotropic glutamate receptor homo- and heterodimers exhibit distinct responses to orthosteric and allosteric ligands

代谢型谷氨酸受体同源二聚体和异源二聚体对正构配体和变构配体表现出不同的反应。

McCullock, Tyler W; Couch, Tyler; Kammermeier, Paul J

Proline substitutions in the ASIC1 β11-12 linker slow desensitization.

ASIC1 β11-12 连接子中的脯氨酸取代会减缓脱敏作用

Purohit Rutambhara, Couch Tyler, Rook Matthew L, MacLean David M

Photomodulation of the ASIC1a acidic pocket destabilizes the open state.

ASIC1a酸性口袋的光调制会破坏其开放状态

Rook Matthew L, McCullock Tyler W, Couch Tyler, Lueck John D, MacLean David M

Topography and motion of acid-sensing ion channel intracellular domains

酸敏感离子通道胞内结构域的形貌和运动

Couch, Tyler; Berger, Kyle D; Kneisley, Dana L; McCullock, Tyler W; Kammermeier, Paul; Maclean, David M

The Methyltransferase Setd8 Is Essential for Erythroblast Survival and Maturation

甲基转移酶Setd8对成红细胞的存活和成熟至关重要

Malik, Jeffrey; Lillis, Jacquelyn A; Couch, Tyler; Getman, Michael; Steiner, Laurie A