日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Prediction of higher ceftazidime-avibactam concentrations in the human renal interstitium compared with unbound plasma using a minimal physiologically based pharmacokinetic model developed in rats and pigs through microdialysis

利用在大鼠和猪体内建立的基于生理的最小药代动力学模型，通过微透析预测人肾间质中头孢他啶-阿维巴坦的浓度高于游离血浆中的浓度。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01518-24
Vallée, Maxime; Aranzana-Climent, Vincent; Moreau, Jérémy; Lamarche, Isabelle; Fontanier, Théo; Barc, Céline; Kasal-Hoc, Nathalie; Debiais-Delpech, Céline; Mirfendereski, Hélène; Pezant, Jérémy; Pinard, Anne; Clarhaut, Jonathan; Couet, William; Cazenave-Roblot, France; Marchand, Sandrine
Rat
发表日期：2025
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In vitro pharmacokinetic/pharmacodynamic modeling of the effect of mucin on polymyxin B activity against Acinetobacter baumannii

体外药代动力学/药效学模型研究粘蛋白对多粘菌素B抗鲍曼不动杆菌活性的影响

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01535-24
Lacroix, Mathilde; Moreau, Jérémy; Zampaloni, Claudia; Bissantz, Caterina; Mirfendereski, Hélène; Shirvani, Hamasseh; Marchand, Sandrine; Couet, William; Chauzy, Alexia
发表日期：2025
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The synergistic effect of the combination of polymyxin B and rifampicin in a murine neutropenic thigh infection model with E. coli and K. pneumoniae.

在小鼠中性粒细胞减少性大腿感染大肠杆菌和肺炎克雷伯菌模型中，多粘菌素 B 和利福平联合用药具有协同作用

期刊:Journal of Antimicrobial Chemotherapy
影响因子:3.6
doi:10.1093/jac/dkaf056
Van Den Berg Sanne, Sassen Sebastiaan D T, Couet William, Marchand Sandrine, Van Der Spek Heleen, Ten Kate Marian T, Meletiadis Joseph, Muller Anouk E
细胞生物学
肺炎
中性粒细胞
发表日期：2025
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Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling

利用半机制PKPD模型对铜绿假单胞菌在头孢洛扎尼-他唑巴坦治疗过程中观察到的ampC和/或ampD突变引起的耐药性进行表征

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00480-23
Deroche, Luc; Aranzana-Climent, Vincent; Rozenholc, Albane; Prouvensier, Laure; Darnaud, Léa; Grégoire, Nicolas; Marchand, Sandrine; Ploy, Marie-Cécile; François, Bruno; Couet, William; Barraud, Olivier; Buyck, Julien M
发表日期：2023
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Pharmacokinetic and pharmacodynamic properties of polymyxin B in Escherichia coli and Klebsiella pneumoniae murine infection models

多粘菌素B在大肠杆菌和肺炎克雷伯菌小鼠感染模型中的药代动力学和药效学特性

期刊:Journal of Antimicrobial Chemotherapy
影响因子:3.6
doi:10.1093/jac/dkad022
van der Meijden, Aart; Aranzana-Climent, Vincent; van der Spek, Heleen; de Winter, Brenda C M; Couet, William; Meletiadis, Joseph; Muller, Anouk E; van den Berg, Sanne
肺炎
炎症/感染
发表日期：2023
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A Minimal Physiologically Based Pharmacokinetic Model to Characterize CNS Distribution of Metronidazole in Neuro Care ICU Patients

基于生理学的最小药代动力学模型用于表征神经重症监护病房患者中甲硝唑的中枢神经系统分布

期刊:Antibiotics-Basel
影响因子:4.6
doi:10.3390/antibiotics11101293
Chauzy, Alexia; Bouchène, Salim; Aranzana-Climent, Vincent; Clarhaut, Jonathan; Adier, Christophe; Grégoire, Nicolas; Couet, William; Dahyot-Fizelier, Claire; Marchand, Sandrine
神经科学
发表日期：2022
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A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro

一种新的药代动力学-药效学模型用于表征鲍曼不动杆菌接种物对多粘菌素B的体外效应

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01789-21
Akrong, Grace; Chauzy, Alexia; Aranzana-Climent, Vincent; Lacroix, Mathilde; Deroche, Luc; Prouvensier, Laure; Buyck, Julien M; Couet, William; Marchand, Sandrine
发表日期：2022
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Optimized Rhombic Experimental Dynamic Checkerboard Designs to Elucidate Pharmacodynamic Drug Interactions of Antibiotics

优化菱形实验动态棋盘格设计以阐明抗生素的药效学药物相互作用

期刊:Pharmaceutical Research
影响因子:4.3
doi:10.1007/s11095-022-03396-7
Kroemer, Niklas; Aubry, Romain; Couet, William; Grégoire, Nicolas; Wicha, Sebastian G
发表日期：2022
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Activation of class 1 integron integrase is promoted in the intestinal environment

肠道环境会促进1类整合子整合酶的激活。

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1010177
Baltazar, Murielle; Bourgeois-Nicolaos, Nadège; Larroudé, Macarena; Couet, William; Uwajeneza, Solange; Doucet-Populaire, Florence; Ploy, Marie-Cécile; Da Re, Sandra
发表日期：2022
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Lipid Nanoparticles Loaded with Farnesol or Geraniol to Enhance the Susceptibility of E. coli MCR-1 to Colistin

负载法尼醇或香叶醇的脂质纳米颗粒可增强大肠杆菌MCR-1对粘菌素的敏感性

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics13111849
Valcourt, Chantal; Buyck, Julien M; Grégoire, Nicolas; Couet, William; Marchand, Sandrine; Tewes, Frédéric
MCR
发表日期：2021
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