Coughlin Laura相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing CD8 (+) T cell antitumor immunity

肠道菌群来源的胆汁酸可通过增强 CD8(+) T 细胞抗肿瘤免疫力来克服抗生素引起的免疫检查点疗法低反应性。

doi:10.64898/2026.04.15.718788

Li, Wenling; Zarek, Christina M; Wang, Hesuiyuan; Gan, Shuheng; Sabaiefard, Parastoo; Del Valle, Priscilla; Kim, Jiwoong; Poulides, Nicole; Coughlin, Laura A; Lichterman, Jake N; Zhang, Cheng; Chiu, Rebecca Suet-Yan; Srinivasan, Tarun; Velasquez, Mauricio J; Raman, Indu; Maddox, Vanessa J; McDonald, Jeffrey; Kittler, Ralf; Raj, Prithvi; Li, Xin V; Zhan, Xiaowei; Liao, Chen; Xavier, Joao B; Koh, Andrew Y

免疫/内分泌

细胞生物学

发表日期：2026

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Identifying Microbiota and Immune Host Factors Associated With Bleeding Risk in Children With Immune Thrombocytopenia

识别与免疫性血小板减少症患儿出血风险相关的微生物群和免疫宿主因素

期刊:American Journal of Hematology

影响因子:9.9

doi:10.1002/ajh.27669

Saini, Shelly; Sabaeifard, Parastoo; Coughlin, Laura; Poulides, Nicole; Gan, Shuheng; Zhan, Xiaowei; Dang, Mary; Koh, Andrew Y; Zia, Ayesha

免疫/内分泌

发表日期：2025

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Optimizing Precision Probiotics for Mitigating Graft-Versus-Host Disease

优化精准益生菌以减轻移植物抗宿主病

期刊:Microorganisms

影响因子:4.2

doi:10.3390/microorganisms13040706

Ebigbo, Nonyelum; Long, Apple; Do, Phinga; Coughlin, Laura; Poulides, Nicole; Jewell, Talia; Gan, Shuheng; Zhan, Xiaowei; Koh, Andrew Y

发表日期：2025

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Microbiota-derived short-chain fatty acids mediate Candida albicans gastrointestinal colonization resistance

肠道菌群来源的短链脂肪酸介导白色念珠菌对胃肠道定植的抵抗力。

doi:10.1101/2025.09.08.674977

Mishra, Animesh A; Coughlin, Laura A; Poulides, Nicole; Kim, Jiwoong; Zhan, Xiaowei; Gan, Shuheng; Winter, Sebastian E; Zarek, Christina M; Hooper, Lora V; Koh, Andrew Y

发表日期：2025

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Timing of immune checkpoint blockade shapes anti-tumor immunity via a clock-dependent chemokine axis

免疫检查点阻断的时机通过时钟依赖性趋化因子轴塑造抗肿瘤免疫。

doi:10.1101/2025.11.03.686293

Lichterman, Jake N; Srinivasan, Tarun; Wang, Ruheng; Dende, Chaitanya; Zarek, Christina; Ramirez, Josue I; Park, Noheon; Wang, Hesuiyuan; Li, Wenling; Kim, Jiwoong; Coughlin, Laura; Poulides, Nicole; Sabaeifard, Parastoo; Palmer, Suzette N; Morrill, Aidan C; Hassell, Brian; Shelton, John M; Li, Xin V; Evers, Bret M; Zhan, Xiaowei; Takahashi, Joseph S; Hooper, Lora V; Koh, Andrew Y

免疫/内分泌

发表日期：2025

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Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance.

易感细菌在哺乳动物胃肠道中能够耐受抗生素治疗而不产生耐药性

期刊:Cell Host & Microbe

影响因子:18.7

doi:10.1016/j.chom.2024.01.012

Rodrigues Marinelle, Sabaeifard Parastoo, Yildiz Muhammed Sadik, Lyon Adam, Coughlin Laura, Ahmed Sara, Poulides Nicole, Toprak Ahmet C, Behrendt Cassie, Wang Xiaoyu, Monogue Marguerite, Kim Jiwoong, Gan Shuheng, Zhan Xiaowei, Filkins Laura, Williams Noelle S, Hooper Lora V, Koh Andrew Y, Toprak Erdal

发表日期：2024

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Assessment of Distinct Gut Microbiome Signatures in a Diverse Cohort of Patients Undergoing Definitive Treatment for Rectal Cancer

对接受直肠癌根治性治疗的各类患者群体中独特的肠道微生物组特征进行评估

期刊:Journal of Immunotherapy and Precision Oncology

影响因子:3.2

doi:10.36401/JIPO-23-30

Hein, David M; Coughlin, Laura A; Poulides, Nicole; Koh, Andrew Y; Sanford, Nina N

发表日期：2024

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Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

易感细菌在哺乳动物胃肠道中能够耐受抗生素治疗而不产生耐药性。

doi:10.1101/2023.01.11.523617

Rodrigues, Marinelle; Sabaeifard, Parastoo; Yildiz, Muhammed Sadik; Coughlin, Laura; Ahmed, Sara; Behrendt, Cassie; Wang, Xiaoyu; Monogue, Marguerite; Kim, Jiwoong; Gan, Shuheng; Zhan, Xiaowei; Filkins, Laura; Williams, Noelle S; Hooper, Lora V; Koh, Andrew Y; Toprak, Erdal

发表日期：2023

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Transcriptional profiling identifies caspase-1 as a T cell-intrinsic regulator of Th17 differentiation.

转录组分析表明 caspase-1 是 T 细胞内在的 Th17 分化调节因子

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.20190476

Gao Yajing, Deason Krystin, Jain Aakanksha, Irizarry-Caro Ricardo A, Dozmorov Igor, Coughlin Laura A, Rauch Isabella, Evers Bret M, Koh Andrew Y, Wakeland Edward K, Pasare Chandrashekhar

细胞生物学

发表日期：2020

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Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

宏基因组鸟枪法测序和无偏代谢组学分析鉴定出与黑色素瘤患者免疫检查点疗法疗效相关的特定人类肠道微生物群和代谢物

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2017.08.004

Frankel, Arthur E; Coughlin, Laura A; Kim, Jiwoong; Froehlich, Thomas W; Xie, Yang; Frenkel, Eugene P; Koh, Andrew Y

免疫/内分泌

发表日期：2017

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