日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The neuroprotective γ-hydroxybutyrate analog 3-hydroxycyclopent-1-enecarboxylic acid does not directly affect CaMKIIα autophosphorylation at T286 or binding to GluN2B

具有神经保护作用的γ-羟基丁酸类似物3-羟基环戊-1-烯羧酸不直接影响CaMKIIα在T286位点的自磷酸化或与GluN2B的结合。

Brown, Carolyn Nicole; Blaine, Rachel E; Barker, Chase Madison; Coultrap, Steven J; Bayer, Karl Ulrich

Aβ impairs the LTP-related movement of endogenous CaMKII but not of exogenous GFP-CaMKII

Aβ会损害内源性CaMKII的LTP相关运动,但不会影响外源性GFP-CaMKII的运动。

Brown, Carolyn Nicole; Chao, Fan-Yi; Quang, Daphne; Rumian, Nicole L; Kleinjan, Mason S; Coultrap, Steven J; Bayer, K Ulrich

The CaMKII D135N mutation blocks kinase activity and reduces GluN2B binding

CaMKII D135N 突变会阻断激酶活性并降低 GluN2B 的结合。

Larsen, Matthew E; Barker, C Madison; Vargas, Raul Satoshi; Coultrap, Steven J; Bayer, K Ulrich

CaMKII monomers are sufficient for GluN2B binding, co-condensation, and synaptic potentiation.

CaMKII 单体足以与 GluN2B 结合、共凝聚和突触增强

Brown Carolyn Nicole, Barker C Madison, Miller Carley N, Aoto Jason, Coultrap Steven J, Bayer K Ulrich

LTP expression mediated by autonomous activity of GluN2B-bound CaMKII.

LTP表达由GluN2B结合的CaMKII的自主活性介导

Rumian Nicole L, Barker C Madison, Larsen Matthew E, Tullis Jonathan E, Freund Ronald K, Taslimi Amir, Coultrap Steven J, Tucker Chandra L, Dell'Acqua Mark L, Bayer K Ulrich

LTP induction by structural rather than enzymatic functions of CaMKII

CaMKII 的结构功能而非酶功能诱导 LTP

Tullis, Jonathan E; Larsen, Matthew E; Rumian, Nicole L; Freund, Ronald K; Boxer, Emma E; Brown, Carolyn Nicole; Coultrap, Steven J; Schulman, Howard; Aoto, Jason; Dell'Acqua, Mark L; Bayer, K Ulrich

Decreased nitrosylation of CaMKII causes aging-associated impairments in memory and synaptic plasticity in mice

CaMKII亚硝基化水平降低会导致小鼠出现与衰老相关的记忆力和突触可塑性障碍。

Rumian, Nicole L; Freund, Ronald K; Dell'Acqua, Mark L; Coultrap, Steven J; Bayer, K Ulrich

Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events

Aβ 诱导的突触损伤需要通过间接信号事件刺激 CaMKII 活性

Carolyn Nicole Brown, Nicole L Rumian, Jonathan E Tullis, Steven J Coultrap, K Ulrich Bayer

CaMKII holoenzyme mechanisms that govern the LTP versus LTD decision

控制 LTP 与 LTD 决策的 CaMKII 全酶机制

Sarah G Cook, Olivia R Buonarati, Steven J Coultrap, K Ulrich Bayer

Conserved and divergent features of neuronal CaMKII holoenzyme structure, function, and high-order assembly

神经元 CaMKII 全酶结构、功能和高阶组装的保守和发散特征

Olivia R Buonarati, Adam P Miller, Steven J Coultrap, K Ulrich Bayer, Steve L Reichow