日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large neutral amino acid uptake and mTOR activation within CD4 T cells coordinate type 2 immunity and host resistance to Trichuris muris

CD4 T 细胞内大量中性氨基酸的摄取和 mTOR 的激活协调 2 型免疫和宿主对鼠鞭虫的抵抗力。

Krauss, Maria Z; Hayes, Kelly S; Hodge, Suzanne H; Villegas-Mendez, Ana; Hepworth, Matthew R; Sinclair, Linda V; Couper, Kevin N; Grencis, Richard K

Spatial gene regulatory networks driving cell state transitions during human liver disease.

人类肝脏疾病中驱动细胞状态转变的空间基因调控网络

Hammond Nigel L, Murtuza Baker Syed, Georgaka Sokratia, Al-Anbaki Ali, Jokl Elliot, Simpson Kara, Sanchez-Alvarez Rosa, Athwal Varinder S, Purssell Huw, Siriwardena Ajith K, Spiers Harry V M, Dixon Mike J, Bere Leoma D, Jones Adam P, Haley Michael J, Couper Kevin N, Bobola Nicoletta, Sharrocks Andrew D, Hanley Neil A, Rattray Magnus, Piper Hanley Karen

The tumour immune microenvironment is enriched but suppressed in vestibular schwannoma compared to meningioma: therapeutic implications for NF2-related schwannomatosis

与脑膜瘤相比,前庭神经鞘瘤的肿瘤免疫微环境富集但受到抑制:对NF2相关神经鞘瘤病的治疗意义

Gregory, Grace E; Haley, Michael J; Jones, Adam Paul; Zeef, Leo A H; Evans, D Gareth; King, Andrew T; Paszek, Pawel; Couper, Kevin N; Brough, David; Pathmanaban, Omar N

SOX9 plays an essential role in myofibroblast driven hepatic granuloma integrity and parenchymal repair during schistosomiasis-induced liver damage.

SOX9 在血吸虫病引起的肝损伤中,在肌成纤维细胞驱动的肝肉芽肿完整性和实质修复中起着至关重要的作用

Su Kim, Jokl Elliot, Costain Alice, Simpson Kara, Cheeseman Antonn, Phythian-Adams Alexander, Couper Kevin N, MacDonald Andrew S, Piper Hanley Karen

Skull-meninges-brain connectivity and extra-axial brain tumours

颅骨-脑膜-脑连接与轴外脑肿瘤

Islim, Abdurrahman I; Vyziotis, Alexandros; Pathmanaban, Omar N; Coope, David J; King, Andrew T; Brough, David; Jardine, Laura; Couper, Kevin N; Greenhalgh, Andrew D

Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population.

空间分辨单细胞图谱揭示了马拉维人群中致命性肺部 COVID-19 的独特细胞特征

Nyirenda James, Hardy Olympia M, Silva Filho João Da, Herder Vanessa, Attipa Charalampos, Ndovi Charles, Siwombo Memory, Namalima Takondwa Rex, Suwedi Leticia, Ilia Georgios, Nyasulu Watipenge, Ngulube Thokozile, Nyirenda Deborah, Mvaya Leonard, Phiri Joseph, Chasweka Dennis, Eneya Chisomo, Makwinja Chikondi, Phiri Chisomo, Ziwoya Frank, Tembo Abel, Makwangwala Kingsley, Khoswe Stanley, Banda Peter, Morton Ben, Hilton Orla, Lawrence Sarah, Dos Reis Monique Freire, Melo Gisely Cardoso, de Lacerda Marcus Vinicius Guimaraes, Trindade Maranhão Costa Fabio, Monteiro Wuelton Marcelo, Ferreira Luiz Carlos de Lima, Johnson Carla, McGuinness Dagmara, Jambo Kondwani, Haley Michael, Kumwenda Benjamin, Palmarini Massimo, Denno Donna M, Voskuijl Wieger, Kamiza Steve Bvuobvuo, Barnes Kayla G, Couper Kevin, Marti Matthias, Otto Thomas D, Moxon Christopher A

Alternatively activated macrophages are associated with faster growth rate in vestibular schwannoma

替代激活的巨噬细胞与前庭神经鞘瘤的快速生长有关。

Gregory, Grace E; Haley, Michael J; Jones, Adam P; Hannan, Cathal J; Evans, D Gareth; King, Andrew T; Paszek, Pawel; Pathmanaban, Omar N; Couper, Kevin N; Brough, David

Synergistic blockade of TIGIT and PD-L1 increases type-1 inflammation and improves parasite control during murine blood-stage Plasmodium yoelii non-lethal infection

TIGIT 和 PD-L1 的协同阻断可增强 1 型炎症反应,并改善小鼠血液期约氏疟原虫非致死性感染期间的寄生虫控制。

Dookie, Rebecca S; Villegas-Mendez, Ana; Cheeseman, Antonn; Jones, Adam P; Barroso, Ruben; Barrett, Jordan R; Draper, Simon J; Janse, Chris J; Grogan, Jane L; MacDonald, Andrew S; Couper, Kevin N

Ouroboros: cross-linking protein expression perturbations and cancer histology imaging with generative-predictive modeling

Ouroboros:利用生成预测模型将蛋白质表达扰动与癌症组织学成像联系起来

Deshpande, Srijay; Georgaka, Sokratia; Haley, Michael; Sellers, Robert; Minshull, James; Nallala, Jayakrupakar; Fergie, Martin; Stone, Nicholas; Rajpoot, Nasir; Baker, Syed Murtuza; Iqbal, Mudassar; Couper, Kevin; Roncaroli, Federico; Minhas, Fayyaz

Evaluation of 4-Aminoquinoline Hydrazone Analogues as Potential Leads for Drug-Resistant Malaria

评估 4-氨基喹啉腙类似物作为耐药疟疾潜在先导化合物

Magwaza, Rachael N; Abubaker, Muna; Hussain, Buthaina; Haley, Michael; Couper, Kevin; Freeman, Sally; Nirmalan, Niroshini J