日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-a]pyridine Antileishmanial Pharmacophore

提高3-硝基咪唑并[1,2-a]吡啶抗利什曼原虫药效团的水溶性和体外药代动力学性质

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph15080998
Paoli-Lombardo, Romain; Primas, Nicolas; Bourgeade-Delmas, Sandra; Hutter, Sébastien; Sournia-Saquet, Alix; Boudot, Clotilde; Brenot, Emilie; Castera-Ducros, Caroline; Corvaisier, Sophie; Since, Marc; Malzert-Fréon, Aurélie; Courtioux, Bertrand; Valentin, Alexis; Verhaeghe, Pierre; Azas, Nadine; Rathelot, Pascal; Vanelle, Patrice
发表日期：2022
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Design, Synthesis, and Antiprotozoal Evaluation of New Promising 2,9-Bis[(substituted-aminomethyl)]-4,7-phenyl-1,10-phenanthroline Derivatives, a Potential Alternative Scaffold to Drug Efflux

新型有前景的2,9-双[(取代氨甲基)]-4,7-苯基-1,10-菲咯啉衍生物的设计、合成及抗原生动物活性评价，一种潜在的药物外排替代骨架

期刊:Pathogens
影响因子:3.3
doi:10.3390/pathogens11111339
Guillon, Jean; Cohen, Anita; Boudot, Clotilde; Monic, Sarah; Savrimoutou, Solène; Moreau, Stéphane; Albenque-Rubio, Sandra; Lafon-Schmaltz, Camille; Dassonville-Klimpt, Alexandra; Mergny, Jean-Louis; Ronga, Luisa; Bernabeu de Maria, Mikel; Lamarche, Jeremy; Lago, Cristina Dal; Largy, Eric; Gabelica, Valérie; Moukha, Serge; Dozolme, Pascale; Agnamey, Patrice; Azas, Nadine; Mullié, Catherine; Courtioux, Bertrand; Sonnet, Pascal
发表日期：2022
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Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives

新型2,4-双[(取代氨甲基)苯基]喹啉、1,3-双[(取代氨甲基)苯基]异喹啉和2,4-双[(取代氨甲基)苯基]喹唑啉衍生物的设计、合成及抗原生动物活性评价

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2019.1706502
Guillon, Jean; Cohen, Anita; Boudot, Clotilde; Valle, Alessandra; Milano, Vittoria; Das, Rabindra Nath; Guédin, Aurore; Moreau, Stéphane; Ronga, Luisa; Savrimoutou, Solène; Demourgues, Maxime; Reviriego, Elodie; Rubio, Sandra; Ferriez, Sandie; Agnamey, Patrice; Pauc, Cécile; Moukha, Serge; Dozolme, Pascale; Nascimento, Sophie Da; Laumaillé, Pierre; Bouchut, Anne; Azas, Nadine; Mergny, Jean-Louis; Mullié, Catherine; Sonnet, Pascal; Courtioux, Bertrand
发表日期：2020
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New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi

一种新型 8-硝基喹啉酮衍生物对布氏锥虫和克氏锥虫均表现出亚微摩尔级的体外活性。

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.9b00566
Pedron, Julien; Boudot, Clotilde; Brossas, Jean-Yves; Pinault, Emilie; Bourgeade-Delmas, Sandra; Sournia-Saquet, Alix; Boutet-Robinet, Elisa; Destere, Alexandre; Tronnet, Antoine; Bergé, Justine; Bonduelle, Colin; Deraeve, Céline; Pratviel, Geneviève; Stigliani, Jean-Luc; Paris, Luc; Mazier, Dominique; Corvaisier, Sophie; Since, Marc; Malzert-Fréon, Aurélie; Wyllie, Susan; Milne, Rachel; Fairlamb, Alan H; Valentin, Alexis; Courtioux, Bertrand; Verhaeghe, Pierre
发表日期：2020
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Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity

非基因毒性的3-硝基咪唑并[1,2-a]吡啶类化合物是NTR1的底物，在体外显示出强大的抗利什曼原虫活性。

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.8b00347
Fersing, Cyril; Basmaciyan, Louise; Boudot, Clotilde; Pedron, Julien; Hutter, Sébastien; Cohen, Anita; Castera-Ducros, Caroline; Primas, Nicolas; Laget, Michèle; Casanova, Magali; Bourgeade-Delmas, Sandra; Piednoel, Mélanie; Sournia-Saquet, Alix; Belle Mbou, Valère; Courtioux, Bertrand; Boutet-Robinet, Élisa; Since, Marc; Milne, Rachel; Wyllie, Susan; Fairlamb, Alan H; Valentin, Alexis; Rathelot, Pascal; Verhaeghe, Pierre; Vanelle, Patrice; Azas, Nadine
毒理研究
NTR1
发表日期：2019
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Using detergent-enhanced LAMP for African trypanosome detection in human cerebrospinal fluid and implications for disease staging

利用去垢剂增强型LAMP技术检测人脑脊液中的非洲锥虫及其对疾病分期的意义

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0007631
Grab, Dennis J; Nikolskaia, Olga V; Courtioux, Bertrand; Thekisoe, Oriel M M; Magez, Stefan; Bogorad, Maxim; Dumler, J Stephen; Bisser, Sylvie
神经科学
发表日期：2019
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Neopterin and CXCL-13 in Diagnosis and Follow-Up of Trypanosoma brucei gambiense Sleeping Sickness: Lessons from the Field in Angola

新蝶呤和CXCL-13在布氏锥虫冈比亚型昏睡病诊断和随访中的应用：来自安哥拉实地经验

期刊:Biomed Research International
影响因子:2.3
doi:10.1155/2019/6070176
Bonnet, Julien; Vignoles, Philippe; Tiberti, Natalia; Gedeão, Vatunga; Hainard, Alexandre; Turck, Natacha; Josenando, Theophile; Ndung'u, Joseph M; Sanchez, Jean-Charles; Courtioux, Bertrand; Bisser, Sylvie
发表日期：2019
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Toxoplasma gondii Modulates the Host Cell Responses: An Overview of Apoptosis Pathways

弓形虫调节宿主细胞反应：细胞凋亡途径概述

期刊:Biomed Research International
影响因子:2.3
doi:10.1155/2019/6152489
Mammari, Nour; Halabi, Mohamad Adnan; Yaacoub, Souha; Chlala, Hilda; Dardé, Marie-Laure; Courtioux, Bertrand
细胞生物学
凋亡
表观遗传
Apoptosis
发表日期：2019
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Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study

新型8-硝基喹啉-2(1H)-酮类化合物作为NTR生物活化的抗动质体分子：合成、电化学和构效关系研究

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2018.06.001
Pedron, Julien; Boudot, Clotilde; Hutter, Sébastien; Bourgeade-Delmas, Sandra; Stigliani, Jean-Luc; Sournia-Saquet, Alix; Moreau, Alain; Boutet-Robinet, Elisa; Paloque, Lucie; Mothes, Emmanuelle; Laget, Michèle; Vendier, Laure; Pratviel, Geneviève; Wyllie, Susan; Fairlamb, Alan; Azas, Nadine; Courtioux, Bertrand; Valentin, Alexis; Verhaeghe, Pierre
发表日期：2018
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8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases

8-芳基-6-氯-3-硝基-2-(苯磺酰甲基)咪唑并[1,2-a]吡啶类化合物作为强效抗锥虫分子，可被1型硝基还原酶生物活化

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2018.07.064
Fersing, Cyril; Boudot, Clotilde; Pedron, Julien; Hutter, Sébastien; Primas, Nicolas; Castera-Ducros, Caroline; Bourgeade-Delmas, Sandra; Sournia-Saquet, Alix; Moreau, Alain; Cohen, Anita; Stigliani, Jean-Luc; Pratviel, Geneviève; Crozet, Maxime D; Wyllie, Susan; Fairlamb, Alan; Valentin, Alexis; Rathelot, Pascal; Azas, Nadine; Courtioux, Bertrand; Verhaeghe, Pierre; Vanelle, Patrice
发表日期：2018
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