日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.

应用药代动力学/药效学模型连接小鼠抗肿瘤疗效和猴子毒理学数据，以确定白细胞介素-10 Fc融合蛋白的治疗指数

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2022.829063
Yang Zheng, Loy James, Poirson Brian, Dai Yanshan, Rajendran Surendran, Xu Shihua, Spires Vanessa, Gururajan Murali, Lin Zheng, Arbanas Jaren, Carl Stephen, Pace Samantha, Wang Yun, Mehl John, Vasudevan Krishna, Spires Thomas, Novosiadly Ruslan, Coker Shodeinde, Perez Raymond, Covello Kelly, Morin Paul, Graziano Robert, Broz Miranda, Lehman-McKeeman Lois
细胞生物学
肿瘤
Mouse
肿瘤免疫
发表日期：2022
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Heterozygosity for hypoxia inducible factor 1alpha decreases the incidence of thymic lymphomas in a p53 mutant mouse model

在p53突变小鼠模型中，缺氧诱导因子1α的杂合性降低了胸腺淋巴瘤的发生率。

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-08-4223
Bertout, Jessica A; Patel, Shetal A; Fryer, Benjamin H; Durham, Amy C; Covello, Kelly L; Olive, Kenneth P; Goldschmidt, Michael H; Simon, M Celeste
淋巴瘤
发表日期：2009
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The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis

转录因子HIF-1α在生长因子依赖的有氧和无氧糖酵解调控中起着关键作用

期刊:Genes & Development
影响因子:7.7
doi:10.1101/gad.1529107
Lum, Julian J; Bui, Thi; Gruber, Michaela; Gordan, John D; DeBerardinis, Ralph J; Covello, Kelly L; Simon, M Celeste; Thompson, Craig B
信号转导
发表日期：2007
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HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth

HIF-2α调控Oct-4：缺氧对干细胞功能、胚胎发育和肿瘤生长的影响

期刊:Genes & Development
影响因子:7.7
doi:10.1101/gad.1399906
Covello, Kelly L; Kehler, James; Yu, Hongwei; Gordan, John D; Arsham, Andrew M; Hu, Cheng-Jun; Labosky, Patricia A; Simon, M Celeste; Keith, Brian
肿瘤
发育与干细胞
肿瘤免疫
信号转导
干细胞
细胞生物学
发表日期：2006
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Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells

干细胞中缺氧诱导因子1α (HIF-1α) 和HIF-2α转录活性的差异性调控

期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.26.9.3514-3526.2006
Hu, Cheng-Jun; Iyer, Sangeeta; Sataur, Aneesa; Covello, Kelly L; Chodosh, Lewis A; Simon, M Celeste
信号转导
细胞生物学
发育与干细胞
干细胞
发表日期：2006
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Consequences of the historical demography on the global population structure of two highly migratory cosmopolitan marine fishes: the yellowfin tuna (Thunnus albacares) and the skipjack tuna (Katsuwonus pelamis)

历史人口统计学对两种高度洄游性世界性海洋鱼类——黄鳍金枪鱼（Thunnus albacares）和鲣鱼（Katsuwonus pelamis）——全球种群结构的影响

期刊:BMC Evolutionary Biology
影响因子:
doi:10.1186/1471-2148-5-19
Ely, Bert; Viñas, Jordi; Alvarado Bremer, Jaime R; Black, Donna; Lucas, Luciano; Covello, Kelly; Labrie, Alexis V; Thelen, Eric
发表日期：2005
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