日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bioactive lipid-mediated structural and functional regulation of the essential human potassium channel Kir7.1

生物活性脂质介导的人类必需钾通道 Kir7.1 的结构和功能调控

Niu, Qingwei; Vu, Simon; Xu, Yuanjian; Qian, Mingxing; Rudenko, Anastasiia; Ye, Jin; Zeng, Jianwei; Huang, Wei; Covey, Douglas F; Zhang, Rui; Fu, Ziao; Lishko, Polina V

Live-Cell Imaging and Lipidomics of Low-Density Lipoprotein Containing Intrinsically Fluorescent Cholesteryl Esters

含固有荧光胆固醇酯的低密度脂蛋白的活细胞成像和脂质组学研究

Juhl, Alice Dupont; Sprenger, Richard R; Modzel, Maciej; Halder, Senjuti; Szomek, Maria; Akkerman, Vibeke; Xu, Yuanjian; Heegaard, Christian W; Ejsing, Christer S; Covey, Douglas F; Wüstner, Daniel

Target validation uncouples mitochondrial translocator protein from 19-Atriol-mediated inhibition of steroidogenesis and identifies enzymatic targets

靶点验证将线粒体转运蛋白与19-阿特里醇介导的类固醇生成抑制作用解耦,并鉴定出酶靶点。

Zhao, Amy H; Koganti, Prasanthi P; Qian, Mingxing; Garcia, Anthony; O'Day, Patrick; Auchus, Richard J; Covey, Douglas F; Selvaraj, Vimal

A Non-Classical Neuroactive Steroid Exhibiting Potent, Efficacious GABA (A) Receptor Agonism and NMDA Receptor Inhibition

一种非经典神经活性类固醇,具有强效的GABA(A)受体激动作用和NMDA受体抑制作用。

Shu, Hong-Jin; Xu, Yuanjian; Qian, Mingxing; Benz, Ann; Yuede, Carla M; Covey, Douglas F; Zorumski, Charles F; Mennerick, Steven

The orientation of cholesterol's hydroxyl group affects its membrane dynamics and intracellular transport

胆固醇羟基的取向会影响其膜动力学和细胞内运输。

Lauritsen, Line; Pauli, Amanda Therese; Larsen, Miklas P W; Reinholdt, Peter; Scheidt, Holger A; Xu, Yuanjian; Covey, Douglas F; Depta, Laura; Bryce-Rogers, Hogan; Laraia, Luca; Kongsted, Jacob; Wüstner, Daniel

New directions in neurosteroid therapeutics in neuropsychiatry

神经精神病学中神经甾体疗法的新方向

Zorumski, Charles F; Covey, Douglas F; Izumi, Yukitoshi; Evers, Alex S; Maguire, Jamie L; Mennerick, Steven J

Novel Neuroactive Steroid Analogs and Voltage-Dependent Blockers of Ca(V)3.2 Currents, B372 and YX23, Are Effective Anti-Nociceptives with Diminished Sedative Properties in Intact Female Mice

新型神经活性类固醇类似物和电压依赖性Ca(V)3.2电流阻滞剂B372和YX23在完整雌性小鼠中具有有效的镇痛作用,且镇静作用减弱。

Volvovitz, Benjamin; Miah, Rakib; Park, Kibeom; Kim, Jae Hun; Vargas, Raul; Xu, Yuanjiang; Qian, Mingxing; Covey, Douglas F; Todorovic, Slobodan M; Jevtovic-Todorovic, Vesna

Electrophysiological Characterization of Sex-Dependent Hypnosis by an Endogenous Neuroactive Steroid Epipregnanolone

内源性神经活性类固醇表孕烷醇酮介导的性别依赖性催眠的电生理特征

Timic Stamenic, Tamara; Coulter, Ian; Covey, Douglas F; Todorovic, Slobodan M

Comparative electrophysiological study of neuroactive steroid-induced hypnosis in mice: sex and drug-specific differences

小鼠神经活性类固醇诱导催眠的比较电生理学研究:性别和药物特异性差异

Martin, Abigail; Coulter, Ian; Cox, Reginald; Covey, Douglas F; Todorovic, Slobodan M; Timic Stamenic, Tamara

Facilitation of Ca (V) 3.2 channel gating in pain pathways reveals a novel mechanism of serum-induced hyperalgesia

促进疼痛通路中Ca(V)3.2通道的门控揭示了一种血清诱导痛觉过敏的新机制

Sanner, Karolina; Kawell, Sarah; Evans, J Grayson; Elekovic, Vida; Walz, MacKenzie; Joksimovic, Sonja Lj; Joksimovic, Srdjan M; Donald, Rebecca R; Tomic, Maja; Orestes, Peihan; Feseha, Simon; Dedek, Annemarie; Ghodsi, Seyed Mohammadreza; Fallon, Isabella P; Lee, Jeonghan; Hwang, Sung Mi; Hong, Sung Jun; Mayer, John P; Covey, Douglas F; Romano, Carmelo; Timic Stamenic, Tamara; Chemin, Jean; Bourinet, Emmanuel; Poulen, Gaetan; Longon, Nicolas; Vachiery-Lahaye, Florence; Bauchet, Lue; Zorumski, Charles F; Stowell, Michael H B; Hildebrand, Michael E; Eisenmesser, Elan Z; Jevtovic-Todorovic, Vesna; Todorovic, Slobodan M