日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

PAR2 promotes impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference

PAR2 通过干扰 GLUT2 和 Akt 通路，促进 NAFLD 中葡萄糖摄取受损和胰岛素抵抗。

期刊:Hepatology
影响因子:15.8
doi:10.1002/hep.32589
Shearer, Andrew M; Wang, Yanling; Fletcher, Elizabeth K; Rana, Rajashree; Michael, Emily S; Nguyen, Nga; Abdelmalek, Manal F; Covic, Lidija; Kuliopulos, Athan
代谢
信号转导
PAR2
免疫/内分泌
发表日期：2022
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Calpain-1 inhibition attenuates in vivo thrombosis in a humanized model of sickle cell disease

在镰状细胞病的人源化模型中，钙蛋白酶-1抑制剂可减轻体内血栓形成。

期刊:Thrombosis Research
影响因子:3.4
doi:10.1016/j.thromres.2022.01.029
Mithila, Farha; Schwake, Christopher; Fang, Chao; Merrill-Skoloff, Glenn; Covic, Lidija; Fritz, Daniel I; Hanada, Toshihiko; Flaumenhaft, Robert; Chishti, Athar H
细胞生物学
心血管
发表日期：2022
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Lipopeptide Pepducins as Therapeutic Agents

脂肽肽类药物作为治疗剂

期刊:Methods in Molecular Biology
影响因子:
doi:10.1007/978-1-0716-1752-6_21
Michael, Emily; Covic, Lidija; Kuliopulos, Athan
发表日期：2022
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PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled, Phase 2 Study

PAR1（蛋白酶激活受体 1）肽类药物治疗冠状动脉疾病和急性冠脉综合征患者接受心脏导管介入治疗后心肌坏死：一项随机、安慰剂对照的 II 期研究

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.120.315168
Kuliopulos, Athan; Gurbel, Paul A; Rade, Jeffrey J; Kimmelstiel, Carey D; Turner, Susan E; Bliden, Kevin P; Fletcher, Elizabeth K; Cox, Daniel H; Covic, Lidija
信号转导
发表日期：2020
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PAR2 Pepducin-Based Suppression of Inflammation and Itch in Atopic Dermatitis Models

PAR2肽类药物抑制特应性皮炎模型中的炎症和瘙痒

期刊:Journal of Investigative Dermatology
影响因子:5.7
doi:10.1016/j.jid.2018.08.019
Barr, Travis P; Garzia, Chris; Guha, Srijoy; Fletcher, Elizabeth K; Nguyen, Nga; Wieschhaus, Adam J; Ferrer, Lluis; Covic, Lidija; Kuliopulos, Athan
炎症/感染
Immunology/Inflammation
PAR2
炎症
发表日期：2019
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Trace amine-associated receptor 1 (TAAR1) promotes anti-diabetic signaling in insulin-secreting cells

微量胺相关受体1 (TAAR1) 促进胰岛素分泌细胞中的抗糖尿病信号传导

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA118.005464
Michael, Emily S; Covic, Lidija; Kuliopulos, Athan
TAAR1
信号转导
代谢
糖尿病
细胞生物学
免疫/内分泌
发表日期：2019
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Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis

非经典基质金属蛋白酶 1-蛋白酶激活受体 1 信号通路驱动动脉粥样硬化的进展

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.118.310967
Rana, Rajashree; Huang, Tianfang; Koukos, Georgios; Fletcher, Elizabeth K; Turner, Susan E; Shearer, Andrew; Gurbel, Paul A; Rade, Jeffrey J; Kimmelstiel, Carey D; Bliden, Kevin P; Covic, Lidija; Kuliopulos, Athan
信号转导
心血管
动脉粥样硬化
发表日期：2018
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Protease-Activated Receptor 1 as Therapeutic Target in Breast, Lung, and Ovarian Cancer: Pepducin Approach

蛋白酶激活受体1作为乳腺癌、肺癌和卵巢癌的治疗靶点：肽类药物策略

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms19082237
Covic, Lidija; Kuliopulos, Athan
肺癌
肿瘤
肿瘤免疫
信号转导
乳腺癌
卵巢癌
发表日期：2018
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Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease

靶向PAR1的细胞穿透性肽类药物治疗冠状动脉疾病

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.115.306777
Gurbel, Paul A; Bliden, Kevin P; Turner, Susan E; Tantry, Udaya S; Gesheff, Martin G; Barr, Travis P; Covic, Lidija; Kuliopulos, Athan
细胞生物学
发表日期：2016
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Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor Mimetics

利用细胞穿透性受体模拟物对G蛋白偶联受体进行变构激活

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M115.636316
Zhang, Ping; Leger, Andrew J; Baleja, James D; Rana, Rajashree; Corlin, Tiffany; Nguyen, Nga; Koukos, Georgios; Bohm, Andrew; Covic, Lidija; Kuliopulos, Athan
信号转导
细胞生物学
发表日期：2015
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