Mass Spectrometric Analysis of the Active Site Tryptic Peptide of Recombinant O(6)-Methylguanine-DNA Methyltransferase Following Incubation with Human Colorectal DNA Reveals the Presence of an O(6)-Alkylguanine Adductome
重组O(6)-甲基鸟嘌呤-DNA甲基转移酶活性位点胰蛋白酶肽段与人结直肠DNA孵育后的质谱分析揭示了O(6)-烷基鸟嘌呤加合物的存在。
期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.3c00207
Abdelhady, Rasha; Senthong, Pattama; Eyers, Claire E; Reamtong, Onrapak; Cowley, Elizabeth; Cannizzaro, Luca; Stimpson, Joanna; Cain, Kathleen; Wilkinson, Oliver J; Williams, Nicholas H; Barran, Perdita E; Margison, Geoffrey P; Williams, David M; Povey, Andrew C