日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Shared Dispersal Patterns but Contrasting Levels of Gene Flow in Two Anadromous Salmonids Along a Broad Subarctic Coastal Gradient

沿亚北极广阔海岸梯度分布的两种溯河洄游鲑鱼具有相似的扩散模式,但基因流动水平却截然不同

Bouchard, Raphaël; Babin, Charles; Normandeau, Eric; Xuereb, Amanda; Boulanger, Félix; Coxon, Angela; Diamond, Sanford; Fireman, Robert; Lameboy, John; Louttit, Natasha; Natawapineskum, George; Okimaw, Derek; Torio, Dante; Varty, Stephanie; Moore, Jean-Sébastien; Fraser, Dylan; Bernatchez, Louis

Editorial: Advancements in drug development: exploring bi-specific antibodies as promising therapeutic strategies in oncology

社论:药物研发进展:探索双特异性抗体作为肿瘤治疗中极具前景的策略

Weber, Urs M; Bailis, Julie M; Coxon, Angela; Pine, Sharon R; Giaccone, Giuseppe

Dual Inhibition of Angiopoietin-TIE2 and MET Alters the Tumor Microenvironment and Prolongs Survival in a Metastatic Model of Renal Cell Carcinoma

血管生成素-TIE2和MET的双重抑制可改变肾细胞癌转移模型中的肿瘤微环境并延长生存期

Elbanna, May; Orillion, Ashley R; Damayanti, Nur P; Adelaiye-Ogala, Remi; Shen, Li; Miles, Kiersten Marie; Chintala, Sreenivasulu; Ciamporcero, Eric; Ramakrishnan, Swathi; Ku, Sheng-Yu; Rex, Karen; Caenepeel, Sean; Coxon, Angela; Pili, Roberto

MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor

MAPK通路抑制可诱导MET和GAB1水平升高,从而使BRAF突变型黑色素瘤更容易受到肝细胞生长因子的拯救。

Caenepeel, Sean; Cooke, Keegan; Wadsworth, Sarah; Huang, Guo; Robert, Lidia; Moreno, Blanca Homet; Parisi, Giulia; Cajulis, Elaina; Kendall, Richard; Beltran, Pedro; Ribas, Antoni; Coxon, Angela; Hughes, Paul E

The role of angiopoietins as potential therapeutic targets in renal cell carcinoma

血管生成素在肾细胞癌中作为潜在治疗靶点的作用

Wang, Xiaoen; Bullock, Andrea J; Zhang, Liang; Wei, Lin; Yu, Dongyin; Mahagaokar, Kedar; Alsop, David C; Mier, James W; Atkins, Michael B; Coxon, Angela; Oliner, Jon; Bhatt, Rupal S

Identification of the receptor tyrosine kinase c-Met and its ligand, hepatocyte growth factor, as therapeutic targets in clear cell sarcoma

鉴定受体酪氨酸激酶c-Met及其配体肝细胞生长因子为透明细胞肉瘤的治疗靶点

Davis, Ian J; McFadden, Andrew W; Zhang, Yixiang; Coxon, Angela; Burgess, Teresa L; Wagner, Andrew J; Fisher, David E

Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody

血管生成素-1抑制在抑制血管生成和肿瘤生长中的作用具有情境依赖性:对血管生成素-1/2中和肽抗体AMG 386的启示

Coxon, Angela; Bready, James; Min, Hosung; Kaufman, Stephen; Leal, Juan; Yu, Dongyin; Lee, Tani Ann; Sun, Ji-Rong; Estrada, Juan; Bolon, Brad; McCabe, James; Wang, Ling; Rex, Karen; Caenepeel, Sean; Hughes, Paul; Cordover, David; Kim, Haejin; Han, Seog Joon; Michaels, Mark L; Hsu, Eric; Shimamoto, Grant; Cattley, Russell; Hurh, Eunju; Nguyen, Linh; Wang, Shao Xiong; Ndifor, Anthony; Hayward, Isaac J; Falcón, Beverly L; McDonald, Donald M; Li, Luke; Boone, Tom; Kendall, Richard; Radinsky, Robert; Oliner, Jonathan D

Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels

血管生成素-1和血管生成素-2选择性抑制剂对肿瘤血管正常化作用的差异

Falcón, Beverly L; Hashizume, Hiroya; Koumoutsakos, Petros; Chou, Jeyling; Bready, James V; Coxon, Angela; Oliner, Jonathan D; McDonald, Donald M

The growth factor Midkine antagonizes VEGF signaling in vitro and in vivo.

生长因子 Midkine 在体外和体内均能拮抗 VEGF 信号传导

van der Horst Edward Htun, Frank Brendon T, Chinn Lawrence, Coxon Angela, Li Shyun, Polesso Fanny, Slavin Anthony, Ruefli-Brasse Astrid, Wesche Holger