日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Humanization and functional characterization of enhanced coagulation factor IX variants identified through ancestral sequence reconstruction

通过祖先序列重建鉴定的增强型凝血因子IX变体的人源化和功能表征

Coyle, Christopher W; Knight, Kristopher A; Brown, Harrison C; George, Stephan N; Denning, Gabriela; Branella, Gianna M; Childers, Kenneth C; Spiegel, P Clint; Spencer, H Trent; Doering, Christopher B

The 3.2 Ã structure of a bioengineered variant of blood coagulation factor VIII indicates two conformations of the C2 domain.

生物工程改造的血液凝固因子 VIII 变体的 3.2 Ã 结构表明 C2 结构域有两种构象

Smith Ian W, d'Aquino Anne E, Coyle Christopher W, Fedanov Andrew, Parker Ernest T, Denning Gabriela, Spencer Harold Trent, Lollar Pete, Doering Christopher B, Spiegel Paul Clint Jr