日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Serum factors create species-specific barriers to hepatic gene transfer by lipid nanoparticles in liver-humanized mice.

在肝脏人源化小鼠中，血清因子对脂质纳米颗粒介导的肝脏基因转移形成物种特异性屏障

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2025.101470
Stone Daniel, Takeuchi Ryo, Dulin Harrison, Loprieno Michelle A, Strongin Daniel E, Sathees Saraswathi, Cradick Thomas J, Aubert Martine, Roychoudhury Pavitra, Gordon Jennifer, Jerome Keith R
发表日期：2025
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Correction: Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates

更正：CRISPR靶向SIV在非人灵长类动物中的临床前安全性和生物分布

期刊:Gene Therapy
影响因子:4.5
doi:10.1038/s41434-023-00438-6
Burdo, Tricia H; Chen, Chen; Kaminski, Rafal; Sariyer, Ilker K; Mancuso, Pietro; Donadoni, Martina; Smith, Mandy D; Sariyer, Rahsan; Caocci, Maurizio; Liao, Shuren; Liu, Hong; Huo, Wenwen; Zhao, Huaqing; Misamore, John; Lewis, Mark G; Simonyan, Vahan; Thompson, Elaine E; Xu, Ethan Y; Cradick, Thomas J; Gordon, Jennifer; Khalili, Kamel
发表日期：2024
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Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome

嗜热链球菌 CRISPR-Cas9 系统可实现对人类基因组的特异性编辑

期刊:Molecular Therapy
影响因子:12
doi:10.1038/mt.2015.218
Müller, Maximilian; Lee, Ciaran M; Gasiunas, Giedrius; Davis, Timothy H; Cradick, Thomas J; Siksnys, Virginijus; Bao, Gang; Cathomen, Toni; Mussolino, Claudio
Human
发表日期：2016
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TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

TALENs促进气道上皮黏膜下腺细胞来源的CF-iPSCs中F508del CFTR的单步无缝SDF校正

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1038/mtna.2015.43
Suzuki, Shingo; Sargent, R Geoffrey; Illek, Beate; Fischer, Horst; Esmaeili-Shandiz, Alaleh; Yezzi, Michael J; Lee, Albert; Yang, Yanu; Kim, Soya; Renz, Peter; Qi, Zhongxia; Yu, Jingwei; Muench, Marcus O; Beyer, Ashley I; Guimarães, Alessander O; Ye, Lin; Chang, Judy; Fine, Eli J; Cradick, Thomas J; Bao, Gang; Rahdar, Meghdad; Porteus, Matthew H; Shuto, Tsuyoshi; Kai, Hirofumi; Kan, Yuet W; Gruenert, Dieter C
CFTR
细胞生物学
发表日期：2016
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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

CRISPR/Cas9系统存在脱靶活性，会在靶DNA和引导RNA序列之间造成插入或缺失。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gku402
Lin, Yanni; Cradick, Thomas J; Brown, Matthew T; Deshmukh, Harshavardhan; Ranjan, Piyush; Sarode, Neha; Wile, Brian M; Vertino, Paula M; Stewart, Frank J; Bao, Gang
发表日期：2014
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SAPTA: a new design tool for improving TALE nuclease activity

SAPTA：一种用于提高TALE核酸酶活性的新型设计工具

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkt1363
Lin, Yanni; Fine, Eli J; Zheng, Zhilan; Antico, Christopher J; Voit, Richard A; Porteus, Matthew H; Cradick, Thomas J; Bao, Gang
发表日期：2014
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An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

一种在线生物信息学工具预测锌指蛋白和TALE核酸酶的脱靶切割

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkt1326
Fine, Eli J; Cradick, Thomas J; Zhao, Charles L; Lin, Yanni; Bao, Gang
发表日期：2014
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COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

COSMID：用于识别和验证 CRISPR/Cas 脱靶位点的网络工具

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1038/mtna.2014.64
Cradick, Thomas J; Qiu, Peng; Lee, Ciaran M; Fine, Eli J; Bao, Gang
发表日期：2014
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Nanomedicine: tiny particles and machines give huge gains

纳米医学：微小颗粒和机器带来巨大收益

期刊:Annals of Biomedical Engineering
影响因子:5.4
doi:10.1007/s10439-013-0952-x
Tong, Sheng; Fine, Eli J; Lin, Yanni; Cradick, Thomas J; Bao, Gang
发表日期：2014
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ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites

ZFN-site 在基因组中搜索锌指核酸酶靶位点和非靶位点

期刊:BMC Bioinformatics
影响因子:3.3
doi:10.1186/1471-2105-12-152
Cradick, Thomas J; Ambrosini, Giovanna; Iseli, Christian; Bucher, Philipp; McCaffrey, Anton P
发表日期：2011
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