日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer

CDH1 突变的大规模分析定义了一个独特的分子亚群，对胃癌的治疗具有重要意义

期刊:npj Precision Oncology
影响因子:6.8
doi:10.1038/s41698-024-00694-8
Jingyuan Wang, Joanne Xiu, Francesca Battaglin, Hiroyuki Arai, Shivani Soni, Wu Zhang, Richard M Goldberg, Philip A Philip, Andreas Seeber, Jimmy J Hwang, Anthony F Shields, John L Marshall, Igor Astaturov, Tianshu Liu, A Craig Lockhart, W Michael Korn, Lin Shen, Heinz-Josef Lenz
肿瘤
胃癌
发表日期：2024
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The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance

可溶性鸟苷酸环化酶通路受到抑制，可避免雄激素缺乏引起的衰老，并导致去势抵抗的进展

期刊:
影响因子:
doi:10.1101/2023.05.03.537252
Ling Zhang, Clara I Troccoli, Beatriz Mateo-Victoriano, Laura Misiara Lincheta, Erin Jackson, Ping Shu, Trisha Plastini, Wensi Tao, Deukwoo Kwon, Xi Chen, Janaki Sharma, Merce Jorda, James L Gulley, Marijo Bilusic, Albert Craig Lockhart, Annie Beuve, Priyamvada Rai
信号转导
细胞生物学
Senescence
发表日期：2023
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A Combination of SAHA and Quinacrine Is Effective in Inducing Cancer Cell Death in Upper Gastrointestinal Cancers

SAHA 与奎纳克林联合使用可有效诱导上消化道癌症细胞死亡

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-17-1716
Shoumin Zhu, Zheng Chen, Lihong Wang, Dunfa Peng, Abbes Belkhiri, A Craig Lockhart, Wael El-Rifai
细胞生物学
肿瘤
其它细胞
发表日期：2018
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Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies

研究性 Aurora 激酶抑制剂 alisertib 对晚期恶性肿瘤患者 QTc 间期的影响

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-017-0498-0
Zhou, Xiaofei; Nemunaitis, John; Pant, Shubham; Bauer, Todd M; Patel, Manish; Sarantopoulos, John; Craig Lockhart, A; Goodman, Daniel; Huebner, Dirk; Mould, Diane R; Venkatakrishnan, Karthik
信号转导
肿瘤
肿瘤免疫
发表日期：2018
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Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies

利福平、伊曲康唑和埃索美拉唑对晚期恶性肿瘤患者中在研Aurora α激酶抑制剂alisertib药代动力学的影响

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-017-0499-z
Zhou, Xiaofei; Pant, Shubham; Nemunaitis, John; Craig Lockhart, A; Falchook, Gerald; Bauer, Todd M; Patel, Manish; Sarantopoulos, John; Bargfrede, Michael; Muehler, Andreas; Rangachari, Lakshmi; Zhang, Bin; Venkatakrishnan, Karthik
信号转导
肿瘤
肿瘤免疫
发表日期：2018
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A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor-Positive Metastatic Breast Cancer

AKT 抑制剂 MK-2206 联合激素疗法治疗绝经后雌激素受体阳性转移性乳腺癌患者的 I 期研究

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-15-2160
Cynthia X Ma, Cesar Sanchez, Feng Gao, Robert Crowder, Michael Naughton, Timothy Pluard, Allison Creekmore, Zhanfang Guo, Jeremy Hoog, A Craig Lockhart, Austin Doyle, Charles Erlichman, Matthew J Ellis
信号转导
肿瘤
乳腺癌
PI3K/Akt
发表日期：2016
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A Phase I Trial of BKM120 (Buparlisib) in Combination with Fulvestrant in Postmenopausal Women with Estrogen Receptor-Positive Metastatic Breast Cancer

BKM120（Buparlisib）联合氟维司群治疗雌激素受体阳性转移性乳腺癌绝经后女性的 I 期临床试验

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-15-1745
Cynthia X Ma, Jingqin Luo, Michael Naughton, Foluso Ademuyiwa, Rama Suresh, Malachi Griffith, Obi L Griffith, Zachary L Skidmore, Nicholas C Spies, Avinash Ramu, Lee Trani, Timothy Pluard, Gayathri Nagaraj, Shana Thomas, Zhanfang Guo, Jeremy Hoog, Jing Han, Elaine Mardis, Craig Lockhart, Matthew J E
肿瘤
乳腺癌
发表日期：2016
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A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors

口服 MET 抑制剂 AMG 208 对晚期实体瘤成年患者进行的首次人体研究

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.4472
David S Hong, Peter Rosen, A Craig Lockhart, Siqing Fu, Filip Janku, Razelle Kurzrock, Rabia Khan, Benny Amore, Isaac Caudillo, Hongjie Deng, Yuying C Hwang, Robert Loberg, Gataree Ngarmchamnanrith, Darrin M Beaupre, Peter Lee
肿瘤
Human
发表日期：2015
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A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer

UCN-01联合伊立替康治疗转移性三阴性乳腺癌患者的II期研究

期刊:Breast Cancer Research and Treatment
影响因子:3
doi:10.1007/s10549-012-2378-9
Ma, Cynthia X; Ellis, Matthew J C; Petroni, Gina R; Guo, Zhanfang; Cai, Shi-Rong; Ryan, Christine E; Craig Lockhart, A; Naughton, Michael J; Pluard, Timothy J; Brenin, Christiana M; Picus, Joel; Creekmore, Allison N; Mwandoro, Tibu; Yarde, Erin R; Reed, Jerry; Ebbert, Mark; Bernard, Philip S; Watson, Mark; Doyle, Laurence A; Dancey, Janet; Piwnica-Worms, Helen; Fracasso, Paula M
肿瘤
肿瘤免疫
乳腺癌
发表日期：2013
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