日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models

使用磷酸化 tau 抗体进行被动免疫可减少两种不同的小鼠 tau 病变模型中的 tau 病理和功能缺陷

Sethu Sankaranarayanan, Donna M Barten, Laurel Vana, Nino Devidze, Ling Yang, Gregory Cadelina, Nina Hoque, Lynn DeCarr, Stefanie Keenan, Alan Lin, Yang Cao, Bradley Snyder, Bin Zhang, Magdalena Nitla, Gregg Hirschfeld, Nestor Barrezueta, Craig Polson, Paul Wes, Vangipuram S Rangan, Angela Cacace, C

Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780

γ-分泌酶调节剂BMS-869780的鉴定及临床前药理学

Jeremy H Toyn, Lorin A Thompson, Kimberley A Lentz, Jere E Meredith Jr, Catherine R Burton, Sethu Sankaranararyanan, Valerie Guss, Tracey Hall, Lawrence G Iben, Carol M Krause, Rudy Krause, Xu-Alan Lin, Maria Pierdomenico, Craig Polson, Alan S Robertson, R Rex Denton, James E Grace, John Morrison, J

Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027

使用低剂量的微管稳定剂 BMS-241027,tau 转基因小鼠的高动力微管、认知缺陷和病理得到改善

Donna M Barten, Patrizia Fanara, Cathy Andorfer, Nina Hoque, P Y Anne Wong, Kristofor H Husted, Gregory W Cadelina, Lynn B Decarr, Ling Yang, Victoria Liu, Chancy Fessler, Joan Protassio, Timothy Riff, Holly Turner, Christopher G Janus, Sethu Sankaranarayanan, Craig Polson, Jere E Meredith, Gemma Gr