日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Visualizing Mutation-Specific Differences in the Trafficking-Deficient Phenotype of Kv11.1 Proteins Linked to Long QT Syndrome Type 2

可视化与 2 型长 QT 综合征相关的 Kv11.1 蛋白运输缺陷表型中的突变特异性差异

Allison R Hall, Corey L Anderson, Jennifer L Smith, Tooraj Mirshahi, Claude S Elayi, Craig T January, Brian P Delisle

Mouse ERG K(+) channel clones reveal differences in protein trafficking and function

小鼠 ERG K(+) 通道克隆揭示蛋白质运输和功能的差异

Eric C Lin, Brooke M Moungey, Evi Lim, Sarah P Concannon, Corey L Anderson, John W Kyle, Jonathan C Makielski, Sadguna Y Balijepalli, Craig T January

Effect of microculture on cell metabolism and biochemistry: do cells get stressed in microchannels?

微培养对细胞代谢和生物化学的影响:细胞在微通道中会受到压力吗?

Xiaojing Su, Ashleigh B Theberge, Craig T January, David J Beebe

Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum

药物纠正 KCNH2 (hERG) 的长 QT 连锁突变可增加储存在过渡内质网中的 Kv11.1 通道的运输

Jennifer L Smith, Allison R Reloj, Parvathi S Nataraj, Daniel C Bartos, Elizabeth A Schroder, Arthur J Moss, Seiko Ohno, Minoru Horie, Corey L Anderson, Craig T January, Brian P Delisle

Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen

通过体内功能筛选鉴定出长 QT 综合征的新型化学抑制剂

David S Peal, Robert W Mills, Stacey N Lynch, Janet M Mosley, Evi Lim, Patrick T Ellinor, Craig T January, Randall T Peterson, David J Milan

Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER

与长 QT 综合征相关的运输缺陷型 hERG K⁺ 通道受内质网中微管依赖性质量控制隔室的调节

Jennifer L Smith, Christie M McBride, Parvathi S Nataraj, Daniel C Bartos, Craig T January, Brian P Delisle

Small GTPase Rab11b regulates degradation of surface membrane L-type Cav1.2 channels

小 GTPase Rab11b 调节表面膜 L 型 Cav1.2 通道的降解

Jabe M Best, Jason D Foell, Courtney R Buss, Brian P Delisle, Ravi C Balijepalli, Craig T January, Timothy J Kamp

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

高纯度人类诱导多能干细胞衍生的心肌细胞:动作电位和离子电流的电生理特性

Junyi Ma, Liang Guo, Steve J Fiene, Blake D Anson, James A Thomson, Timothy J Kamp, Kyle L Kolaja, Bradley J Swanson, Craig T January

Microfluidic cell culture and its application in high-throughput drug screening: cardiotoxicity assay for hERG channels

微流控细胞培养及其在高通量药物筛选中的应用:hERG 通道的心脏毒性测定

Xiaojing Su, Edmond W K Young, Heather A S Underkofler, Timothy J Kamp, Craig T January, David J Beebe

Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current

婴儿猝死综合征中发现的 Alpha1-syntrophin 突变导致晚期心脏钠电流增加

Jianding Cheng, David W Van Norstrand, Argelia Medeiros-Domingo, Carmen Valdivia, Bi-hua Tan, Bin Ye, Stacie Kroboth, Matteo Vatta, David J Tester, Craig T January, Jonathan C Makielski, Michael J Ackerman