Retrograde flow and myosin II activity within the leading cell edge deliver F-actin to the lamella to seed the formation of graded polarity actomyosin II filament bundles in migrating fibroblasts.

前缘细胞内的逆行流动和肌球蛋白 II 活性将 F-肌动蛋白输送到片层，从而在迁移的成纤维细胞中形成梯度极性肌动球蛋白 II 丝束