日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dietary sulfur amino acid restriction improves glucose homeostasis through hepatic de novo serine synthesis

限制膳食中含硫氨基酸的摄入可通过肝脏从头合成丝氨酸来改善葡萄糖稳态。

Ortega, Andres F; Vang, Cha Mee; Rome, Ferrol I; Andreoni, Kaitlyn M; Phoebe, Aiden M; Nelson, Alisa B; Crawford, Peter A; Galligan, James J; Huang, Stanley Ching-Cheng; Hughey, Curtis C

Cognitive impairment caused by compromised hepatic ketogenesis is prevented by endurance exercise

耐力运动可以预防由肝脏酮体生成受损引起的认知障碍。

Kelty, Taylor J; Kerr, Nathan R; Chou, Chih H; Shryack, Grace E; Taylor, Christopher L; Krause, Alexa A; Knutson, Alexandra R; Bunten, Josh; Childs, Tom E; Meers, Grace M; Dashek, Ryan J; Puchalska, Patrycja; Crawford, Peter A; Thyfault, John P; Booth, Frank W; Rector, R Scott

Effects of Time-Restricted Eating on Ketone Metabolism and Immunoregulation in Premenopausal Women: Protocol for a Pilot, Prospective, Single-Arm Dietary Intervention Study

限时饮食对绝经前女性酮体代谢和免疫调节的影响:一项前瞻性单组饮食干预试点研究方案

Thota, Geethika P; Macheret, Natalie A; Glaros, Sophia B; Kacker, Ila N; Cantor, Samson L; Mabundo, Lilian; Malandrino, Noemi; Chen, Kong Y; Courville, Amber B; Turner, Sara; Yang, Shanna; Krenek, Andrea; Recupero, Thomas C; Klein, Rachael J; Han, Kim; Puchalska, Patrycja; Crawford, Peter; Sack, Michael N; Chung, Stephanie T

Ongoing lymphoid HIV production drives pyroptosis and GLP-1 counter-regulation in ART-suppressed infection

持续的淋巴细胞 HIV 生成驱动细胞焦亡和 GLP-1 反调节,从而抑制抗逆转录病毒疗法(ART)感染中的 HIV 细胞。

Crawford, Peter A; Rhein, Joshua; Chipman, Jeffrey G; Beilman, Gregory J; Cromarty, Ross; Escandón, Kevin; Anderson, Jodi; Wieking, Garritt; Johnston, Andrew; Ahmed, Afeefa; Reichel, Jarrett; Khoruts, Alexander; Basting, Christopher M; Kuchma, Nataliia; Baker, Jason V; Klatt, Nichole R; Haase, Ashley T; Schacker, Timothy W

Hepatic ketogenesis supports liver lipid homeostasis during acute exercise but is not required for exercise training to mitigate liver steatosis in mice

肝脏酮体生成在急性运动期间支持肝脏脂质稳态,但并非运动训练减轻小鼠肝脂肪变性的必要条件。

Vang, Cha Mee; Ortega, Andres F; Pfeiffer, Ruth E; Hartmann, Jared L; Hampton, Griffin S; Wang, Hu; Queathem, Eric D; Crawford, Peter A; Han, Xianlin; Hughey, Curtis C

Dietary restriction reprograms CD8(+) T cell fate to enhance anti-tumour immunity and immunotherapy responses.

饮食限制可重编程 CD8(+) T 细胞的命运,从而增强抗肿瘤免疫和免疫治疗反应。

Oswald Brandon M, DeCamp Lisa M, Longo Joseph, Dahabieh Michael S, Bunda Nicholas, Johnson Benjamin K, Watson McLane J, Ma Shixin, Preston Samuel E J, Sheldon Ryan D, Vincent Michael P, Ellis Abigail E, Soper-Hopper Molly T, Isaguirre Christine, Kamarudin Dahlya, Shen Hui, Williams Kelsey S, Crawford Peter A, Kaech Susan, Jang H Josh, Lien Evan C, Krawczyk Connie M, Jones Russell G

Ketogenesis mitigates metabolic dysfunction-associated steatotic liver disease through mechanisms that extend beyond fat oxidation

生酮作用通过除脂肪氧化之外的多种机制来缓解代谢功能障碍相关的脂肪肝疾病。

Queathem, Eric D; Stagg, David B; Nelson, Alisa B; Chaves, Alec B; Crown, Scott B; Fulghum, Kyle; d'Avignon, D Andre; Ryder, Justin R; Bolan, Patrick J; Hayir, Abdirahman; Gillingham, Jacob R; Jannatpour, Shannon; Rome, Ferrol I; Williams, Ashley S; Muoio, Deborah M; Ikramuddin, Sayeed; Hughey, Curtis C; Puchalska, Patrycja; Crawford, Peter A

Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion

乙酰辅酶A羧化酶1抑制剂通过线粒体融合增强Treg细胞代谢和移植物抗宿主病治疗效果。

McDonald-Hyman, Cameron; Aguilar, Ethan G; Compeer, Ewoud B; Zaiken, Michael C; Rhee, Stephanie Y; Mohamed, Fathima A; Larson, Jemma H; Loschi, Michael L; Lees, Christopher; Thangavelu, Govindarajan; Sleeth, Margaret L; Smith, Kyle D; Whangbo, Jennifer S; Ritz, Jerome; Sparwasser, Tim D; O'Connor, Roddy S; Crawford, Peter A; Rathmell, Jeffrey C; Kean, Leslie S; Zeiser, Robert; Hippen, Keli L; Dustin, Michael L; Blazar, Bruce R

Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation.

酮体生成通过脂肪酸延长来维持肝脏多不饱和脂肪酸的稳态

Queathem Eric D, Moazzami Zahra, Stagg David B, Nelson Alisa B, Fulghum Kyle, Hayir Abdirahman, Seay Alisha, Gillingham Jacob R, d'Avignon D André, Han Xianlin, Ruan Hai-Bin, Crawford Peter A, Puchalska Patrycja

Deciphering Colorectal Cancer-Hepatocyte Interactions: A Multiomics Platform for Interrogation of Metabolic Crosstalk in the Liver-Tumor Microenvironment.

解析结直肠癌-肝细胞相互作用:用于研究肝肿瘤微环境中代谢串扰的多组学平台

Nelson Alisa B, Reese Lyndsay E, Rono Elizabeth, Queathem Eric D, Qiu Yinjie, McCluskey Braedan M, Crampton Alexandra, Conniff Eric, Cummins Katherine, Boytim Ella, Dansou Senali, Hwang Justin, Safo Sandra E, Puchalska Patrycja, Wood David K, Schwertfeger Kathryn L, Crawford Peter A