日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacologic or genetic interference with atrogene signaling protects against glucocorticoid-induced musculoskeletal and cardiac disease

通过药物或基因手段干扰萎缩基因信号传导,可以预防糖皮质激素诱发的肌肉骨骼和心脏疾病。

Sato, Amy Y; Cregor, Meloney; McAndrews, Kevin; Schurman, Charles A; Schaible, Eric; Shutter, Jennifer; Vyas, Punit; Adhikari, Bhawana; Willis, Monte S; Boerma, Marjan; Alliston, Tamara; Bellido, Teresita

Reversal of the diabetic bone signature with anabolic therapies in mice

利用合成代谢疗法逆转小鼠的糖尿病骨质特征

Silvia Marino, Nisreen Akel, Shenyang Li, Meloney Cregor, Meghan Jones, Betiana Perez, Gaston Troncoso, Jomeeka Meeks, Scott Stewart, Amy Y Sato, Intawat Nookaew, Teresita Bellido

Notch3 signaling between myeloma cells and osteocytes in the tumor niche promotes tumor growth and bone destruction

骨髓瘤细胞与肿瘤微环境内的骨细胞之间的 Notch3 信号传导促进肿瘤生长和骨质破坏

Hayley M Sabol, Tânia Amorim, Cody Ashby, David Halladay, Judith Anderson, Meloney Cregor, Megan Sweet, Intawat Nookaew, Noriyoshi Kurihara, G David Roodman, Teresita Bellido, Jesus Delgado-Calle

Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity

将 Notch 抑制剂靶向骨髓瘤骨髓微环境可减少肿瘤生长和骨质破坏,且无肠道毒性

Hayley M Sabol #, Adam J Ferrari #, Manish Adhikari, Tânia Amorim, Kevin McAndrews, Judith Anderson, Michele Vigolo, Rajwinder Lehal, Meloney Cregor, Sharmin Khan, Pedro L Cuevas, Jill A Helms, Noriyoshi Kurihara, Venkat Srinivasan, Frank H Ebetino, Robert K Boeckman Jr, G David Roodman, Teresita Be

Genetic deletion of Sost or pharmacological inhibition of sclerostin prevent multiple myeloma-induced bone disease without affecting tumor growth

基因敲除Sost或药物抑制硬骨蛋白可预防多发性骨髓瘤引起的骨病,且不影响肿瘤生长。

Delgado-Calle, J; Anderson, J; Cregor, M D; Condon, K W; Kuhstoss, S A; Plotkin, L I; Bellido, T; Roodman, G D

Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases

糖皮质激素通过E3泛素连接酶上游的组织特异性机制诱导骨骼和肌肉萎缩

Sato, Amy Y; Richardson, Danielle; Cregor, Meloney; Davis, Hannah M; Au, Ernie D; McAndrews, Kevin; Zimmers, Teresa A; Organ, Jason M; Peacock, Munro; Plotkin, Lilian I; Bellido, Teresita

Nrf2 regulates mass accrual and the antioxidant endogenous response in bone differently depending on the sex and age

Nrf2 对骨骼质量积累和抗氧化内源性反应的调节作用因性别和年龄而异。

Pellegrini, Gretel Gisela; Cregor, Meloney; McAndrews, Kevin; Morales, Cynthya Carolina; McCabe, Linda Doyle; McCabe, George P; Peacock, Munro; Burr, David; Weaver, Connie; Bellido, Teresita

Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin

在缺乏骨硬化蛋白/硬骨蛋白的情况下,抗分解代谢信号传导可保护骨骼免受糖皮质激素诱导的骨质疏松症的影响。

Sato, Amy Y; Cregor, Meloney; Delgado-Calle, Jesus; Condon, Keith W; Allen, Matthew R; Peacock, Munro; Plotkin, Lilian I; Bellido, Teresita