日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Syngap1 promotes cognitive function through regulation of cortical sensorimotor dynamics

Syngap1通过调节皮层感觉运动动力学来促进认知功能

Vaissiere, Thomas; Michaelson, Sheldon D; Creson, Thomas; Goins, Jessie; Fürth, Daniel; Balazsfi, Diana; Rojas, Camilo; Golovin, Randall; Meletis, Konstantinos; Miller, Courtney A; O'Connor, Daniel; Fontolan, Lorenzo; Rumbaugh, Gavin

Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics

Syngap1通过调节皮层感觉运动动力学促进认知功能

Vaissiere, Thomas; Michaelson, Sheldon D; Creson, Thomas; Goins, Jessie; Fürth, Daniel; Balazsfi, Diana; Rojas, Camilo; Golovin, Randall; Meletis, Konstantinos; Miller, Courtney A; O'Connor, Daniel; Fontolan, Lorenzo; Rumbaugh, Gavin

Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protection

内源性 Syngap1 α 剪接形式促进认知功能和癫痫发作保护

Murat Kilinc, Vineet Arora, Thomas K Creson, Camilo Rojas, Aliza A Le, Julie Lauterborn, Brent Wilkinson, Nicolas Hartel, Nicholas Graham, Adrian Reich, Gemma Gou, Yoichi Araki, Àlex Bayés, Marcelo Coba, Gary Lynch, Courtney A Miller, Gavin Rumbaugh

Re-expression of SynGAP protein in adulthood improves translatable measures of brain function and behavior

SynGAP 蛋白在成年期的重新表达可改善大脑功能和行为的可转化指标

Thomas K Creson #, Camilo Rojas #, Ernie Hwaun, Thomas Vaissiere, Murat Kilinc, Andres Jimenez-Gomez, Jimmy Lloyd Holder Jr, Jianrong Tang, Laura L Colgin, Courtney A Miller, Gavin Rumbaugh

Species-conserved SYNGAP1 phenotypes associated with neurodevelopmental disorders

与神经发育障碍相关的物种保守的SYNGAP1表型

Kilinc, Murat; Creson, Thomas; Rojas, Camilo; Aceti, Massimiliano; Ellegood, Jacob; Vaissiere, Thomas; Lerch, Jason P; Rumbaugh, Gavin

Syngap1 haploinsufficiency damages a postnatal critical period of pyramidal cell structural maturation linked to cortical circuit assembly

Syngap1单倍体不足会损害与皮层回路组装相关的锥体细胞结构成熟的关键出生后时期。

Aceti, Massimiliano; Creson, Thomas K; Vaissiere, Thomas; Rojas, Camilo; Huang, Wen-Chin; Wang, Ya-Xian; Petralia, Ronald S; Page, Damon T; Miller, Courtney A; Rumbaugh, Gavin

Input-specific regulation of hippocampal circuit maturation by non-muscle myosin IIB

非肌肉肌球蛋白IIB对海马回路成熟的输入特异性调控

Emin D Ozkan ,Massimiliano Aceti ,Thomas K Creson ,Camilo S Rojas ,Christopher R Hubbs ,Megan N McGuire ,Priyanka P Kakad ,Courtney A Miller ,Gavin Rumbaugh

Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons

Syngap1突变体认知能力下降是由发育中的前脑兴奋性神经元内的孤立性损伤引起的。

Ozkan, Emin D; Creson, Thomas K; Kramár, Enikö A; Rojas, Camilo; Seese, Ron R; Babyan, Alex H; Shi, Yulin; Lucero, Rocco; Xu, Xiangmin; Noebels, Jeffrey L; Miller, Courtney A; Lynch, Gary; Rumbaugh, Gavin

Emergence of anxiety-like behaviours in depressive-like Cpe(fat/fat) mice

抑郁样Cpe(fat/fat)小鼠出现焦虑样行为

Rodriguiz, Ramona M; Wilkins, John J; Creson, Thomas K; Biswas, Reeta; Berezniuk, Iryna; Fricker, Arun D; Fricker, Lloyd D; Wetsel, William C

Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses

致病性SYNGAP1突变会破坏树突棘突触的成熟,从而损害认知发育。

Clement, James P; Aceti, Massimiliano; Creson, Thomas K; Ozkan, Emin D; Shi, Yulin; Reish, Nicholas J; Almonte, Antoine G; Miller, Brooke H; Wiltgen, Brian J; Miller, Courtney A; Xu, Xiangmin; Rumbaugh, Gavin