日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification and Characterization of ERK2 Dimerization Inhibitors by Integrated In Silico and In Vitro Screening

通过计算机模拟和体外筛选相结合的方法鉴定和表征ERK2二聚化抑制剂

Ortiz-González, Carmen; Casar, Berta; Gozalbes, Rafael; Serrano-Candelas, Eva; Crespo, Piero; Carpio, Laureano E

Editorial: Ras and Other GTPases in Cancer: From Basic to Applied Research

社论:Ras 和其他 GTP 酶在癌症中的作用:从基础研究到应用研究

Cho, Kwang-Jin; Liang, Jin Rui; Crespo, Piero; Aran, Veronica

RAS Dimers: The Novice Couple at the RAS-ERK Pathway Ball

RAS二聚体:RAS-ERK通路舞会上的新手夫妇

Herrero, Ana; Crespo, Piero

Vav mediates Ras stimulation by direct activation of the GDP/GTP exchange factor Ras GRP1

Vav 通过直接激活 GDP/GTP 交换因子 Ras GRP1 来介导 Ras 刺激。

Caloca, María J; Zugaza, José L; Matallanas, David; Crespo, Piero; Bustelo, Xosé R

RAS GTPase-dependent pathways in developmental diseases: old guys, new lads, and current challenges

RAS GTP酶依赖性通路在发育性疾病中的作用:老生常谈、新近涌现以及当前挑战

Bustelo, Xosé R; Crespo, Piero; Fernández-Pisonero, Isabel; Rodríguez-Fdez, Sonia

Correction for Agudo-Ibáñez et al., "H-Ras Distribution and Signaling in Plasma Membrane Microdomains Are Regulated by Acylation and Deacylation Events"

对 Agudo-Ibáñez 等人的论文“H-Ras 在质膜微区中的分布和信号传导受酰化和去酰化事件的调控”的更正

Agudo-Ibáñez, Lorena; Herrero, Ana; Barbacid, Mariano; Crespo, Piero

Defined spatiotemporal features of RAS-ERK signals dictate cell fate in MCF-7 mammary epithelial cells

RAS-ERK信号的特定时空特征决定了MCF-7乳腺上皮细胞的命运。

Herrero, Ana; Casar, Berta; Colón-Bolea, Paula; Agudo-Ibáñez, Lorena; Crespo, Piero

Tumors topple when ERKs uncouple

当ERK解偶联时,肿瘤就会消亡。

Herrero, Ana; Crespo, Piero

Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events

Ras,一个活跃于多个舞台的角色:翻译后修饰、本地化和特定位点事件

Arozarena, Imanol; Calvo, Fernando; Crespo, Piero

Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins

Ras亚细胞定位通过对支架蛋白的不同利用,决定了细胞外信号调节激酶1和2的底物特异性。

Casar, Berta; Arozarena, Imanol; Sanz-Moreno, Victoria; Pinto, Adán; Agudo-Ibáñez, Lorena; Marais, Richard; Lewis, Robert E; Berciano, María T; Crespo, Piero