ASK1 limits kidney glucose reabsorption, growth, and mid-late proximal tubule KIM-1 induction when diabetes and Western diet are combined with SGLT2 inhibition.
当糖尿病和西方饮食与 SGLT2 抑制剂相结合时,ASK1 会限制肾脏对葡萄糖的重吸收、生长以及中晚期近端小管 KIM-1 的诱导
期刊:American Journal of Physiology-Renal Physiology
影响因子:3.4
doi:10.1152/ajprenal.00031.2025
Crespo-Masip Maria, Goodluck Helen A, Kim Young Chul, Oe Yuji, Roach Allie M, Kanoo Sadhana, Lopez Natalia, Zhang Haiyan, Badal Shawn S, Vallon Volker