日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

G1405 Ribosomal Methyltransferase-Driven Antibacterial Resistance Affects the 4,5-Disubstituted-2-deoxystreptamine Class of Aminoglycoside Antibiotics

G1405 核糖体甲基转移酶驱动的抗菌耐药性影响 4,5-二取代-2-脱氧链霉胺类氨基糖苷类抗生素

Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David

Synthesis of 3‑C‑Methyl‑d‑Mannopyranoside Derivatives Functionalized at the 3‑Position

3-C-甲基-D-甘露吡喃糖苷衍生物的合成及其在3位的功能化

Abdullayev, Shuay; Sarpe, Vikram A; Crich, David

Endocyclic Trisubstituted Hydroxylamine Isosteres of Basic Amines for ADME Modulation and Reduction of hERG Activity

用于调节 ADME 和降低 hERG 活性的碱性胺的内环三取代羟胺等排体

Khan, Iftikhar; Hettikankanamalage, Asiri A; Cui, Yizhi; Crich, David

The Stereoselectivity of Neighboring Group-Directed Glycosylation Is Concentration-Dependent

邻基导向糖基化的立体选择性与浓度有关

Basu, Pallabita; Crich, David

Intramolecular N-O Bond Formation for the Synthesis of N-Alkyl and N-Aryl Isoxazolidines

分子内NO键形成合成N-烷基和N-芳基异噁唑烷

Solecki, Margaret; Crich, David

Why Are 5-Thioglycopyranosyl Donors More Axially Selective than their Glycopyranosyl Counterparts? A Low and Variable Temperature NMR Spectroscopy and Computational Study

为什么 5-硫代吡喃糖基供体比其吡喃糖基对应物具有更高的轴向选择性?低温变温核磁共振波谱和计算研究

Ahiadorme, Daniil; Givhan, R Houston; Schaefer, Henry F 3rd; Crich, David

Commonality of Mechanism in Glycoside Hydrolases, Nucleoside Hydrolases, and Phosphorylases: Importance of Side-Chain Conformation Preorganization

糖苷水解酶、核苷水解酶和磷酸化酶的共性机制:侧链构象预组织的重要性

Tseng, Po-Sen; Quirke, Jonathan C K; Lin, W Jonathan; Crich, David

Synthesis of Methyl Aprabiosaminide and 2-Hydroxyapramycin from Apramycin

由阿普拉霉素合成甲基阿普拉比索胺和2-羟基阿普拉霉素

Kasdekar, Niteshlal; Spieker, Michael R; Vasella, Andrea; Hobbie, Sven N; Crich, David

Microwave-Assisted Neutral Glycosylation Reactions in the Absence of Reagent Activators

微波辅助中性糖基化反应(无需试剂活化剂)

Gamage, Shanika M P; Valentin, Geraud; Ghosh, Samir; Eradi, Pradheep; Bagul, Rahul S; Crich, David; Andreana, Peter R

Mechanism of 3-O-Acyl-Directed α-Mannopyranosylation and Rationalization of the Contrasting Behavior of 3-O-Acyl Glucopyranosyl Donors

3-O-酰基导向的α-甘露糖吡喃糖基化反应机理及3-O-酰基葡萄糖吡喃糖基供体不同行为的合理化

Abdullayev, Shuay; Crich, David