日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization

单次注射免疫后,恒河猴V2顶端敲入小鼠模型迅速获得HIV-1中和广度

Ghosh, Amrit Raj; Habib, Rumi; Mishra, Nitesh; Roark, Ryan S; Akauliya, Madhav; Albowaidey, Ali A; Allen, Joel D; Amereh, Khaled; Avillion, Gabriel; Bottermann, Maria; Liang, Bo; Chaudhary, Namit; Callaghan, Sean; Dye, Jonathan; Li, Xuduo; Ellis-Pugh, Jordan R; Roy Chowdhury, Rohan; James, Nicole E; Liu, Xiaotie; Maiorino, Laura; Villavicencio, Paula M; Nedellec, Rebecca; Oberoi, Prabhgun; Sowers, Kirsten J; Park, Younghoon; Prum, Thavaleak; Rodriguez, Linette; Ssozi, Maria; Torres, Jonathan L; Walsh, Agnes A; Warner, John E; Weldon, Stephanie R; Xu, Liling; Wiehe, Kevin; Crispin, Max; Ward, Andrew B; Nair, Usha; Hahn, Beatrice H; Burton, Dennis R; Shapiro, Lawrence; Kwong, Peter D; Irvine, Darrell J; Andrabi, Raiees; Shaw, George M; Batista, Facundo D

Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design.

天然可溶性 E1E2 糖蛋白异二聚体在自组装蛋白纳米颗粒上的应用,用于丙型肝炎病毒疫苗设计。

He Linling, Lee Yi-Zong, Zhang Yi-Nan, Newby Maddy L, Janus Benjamin M, Gonzalez Fabrizio G, Ward Garrett, DesRoberts Connor, Hung Shr-Hau, Giang Erick, Allen Joel D, Kulakova Liudmila, Toth Eric A, Fuerst Thomas R, Law Mansun, Ofek Gilad, Crispin Max, Zhu Jiang

Signatures of native-like glycosylation in RNA replicon-derived HIV-1 immunogens

RNA复制子衍生HIV-1免疫原中天然样糖基化的特征

Chawla, Himanshi; Willcox, Jacob T; Hayes, Grace M; Silva, Murillo; Lee, Wen-Hsin; Ozorowski, Gabriel; Butler, John; Mckay, Paul F; Shattock, Robin J; Ward, Andrew B; Irvine, Darrell J; Crispin, Max

Decoding epitope immunodominance in HIV Env using cryoEM and machine learning

利用冷冻电镜和机器学习解码 HIV Env 中的表位免疫优势

Schuhmacher, Jan S; Xiao, Shuhao; Eray, Elise R; Brown, Sharidan; Zambrowski, Alexander; Jain, Aryan; Garcia, Daniel Montiel; Ozorowski, Gabriel; Zhu, Wenwen; Saam, Katrina; Caniels, Tom G; Moore, John P; Crispin, Max; Sanders, Rogier W; Chakraborty, Srirupa; Correia, Bruno E; Ward, Andrew B; Antanasijevic, Aleksandar

Differential contributions of human oligosaccharyltransferase complexes OST-A and OST-B to HIV-1 envelope glycoprotein glycosylation

人类寡糖基转移酶复合物OST-A和OST-B对HIV-1包膜糖蛋白糖基化的差异性贡献

Atabey, Tugba; Derking, Ronald; Newby, Maddy L; Bouhuijs, Joey H; Snitselaar, Jonne L; Vink, Monique; Aldon, Yoann; Allen, Joel D; Crispin, Max; Sanders, Rogier W

Rational design of next-generation filovirus vaccines combining glycoprotein stabilization and nanoparticle display with glycan modification.

结合糖蛋白稳定化、纳米颗粒展示和糖修饰的下一代丝状病毒疫苗的合理设计。

Lee Yi-Zong, Zhang Yi-Nan, Newby Maddy L, Ward Garrett, Braz Gomes Keegan, Auclair Sarah, DesRoberts Connor, Allen Joel D, Ward Andrew B, Stanfield Robyn L, He Linling, Crispin Max, Wilson Ian A, Zhu Jiang

From sequence to scaffold: Computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks

从序列到支架:基于AlphaFold2预测的结构单元进行蛋白质纳米颗粒疫苗的计算设计

Haas, Cyrus M; Jasti, Naveen; Dosey, Annie; Allen, Joel D; Gillespie, Rebecca; McGowan, Jackson; Leaf, Elizabeth M; Crispin, Max; DeForest, Cole A; Kanekiyo, Masaru; King, Neil P

Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope

HIV包膜蛋白背景下调控抗体FcγR信号传导和效应功能的分子参数

Bick, Michael V; Puig, Eduard; Beauparlant, David; Nedellec, Rebecca; Burton, Iszac; Ardaghi, Keihvan; Zalunardo, Thea R; Bastidas, Raiza; Li, Xuduo; Guenaga, Javier; Lee, Wen-Hsin; Wyatt, Richard; Zhu, Wenwen; Crispin, Max; Ozorowski, Gabriel; Ward, Andrew B; Burton, Dennis R; Hangartner, Lars

Author Correction: Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein

作者更正:免疫原性重组马亚罗病毒样颗粒呈现天然组装的糖蛋白

Kim, Young Chan; Watanabe, Yasunori; Lücke, Arlen-Celina; Song, Xiyong; de Oliveira Souza, Raquel; Stass, Robert; Azar, Sasha R; Rossi, Shannan L; Claser, Carla; Kümmerer, Beate Mareike; Crispin, Max; Bowden, Thomas A; Huiskonen, Juha T; Reyes-Sandoval, Arturo

Harnessing mRNA for the expression of monoclonal IgG and IgA in non-human primates

利用mRNA在非人灵长类动物中表达单克隆IgG和IgA

Rouzeau, Romy; Schmidt, Hayden R; Deal, Cailin E; Allen, Joel D; Dudley, Dawn M; Burton, Iszac; Rakasz, Eva G; Plante, Obadiah; Crispin, Max; Carfi, Andrea; Sok, Devin