Cristian A Lasagna-Reeves相关文献与解析，生知库

Luke C Dabin, Holly Kersey, Byungwook Kim, Dominic J Acri, Daniel Sharify, Audrey Lee-Gosselin, Cristian A Lasagna-Reeves, Adrian L Oblak, Bruce T Lamb, Jungsu Kim

神经

胶质细胞

发表日期：2024

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Enhanced microglial dynamics and a paucity of tau seeding in the amyloid plaque microenvironment contribute to cognitive resilience in Alzheimer's disease

淀粉样斑块微环境中小胶质细胞动力学增强和 tau 播种不足有助于阿尔茨海默病患者的认知恢复能力

期刊:Acta Neuropathologica

影响因子:9.3

doi:10.1007/s00401-024-02775-1

Nur Jury-Garfe, Javier Redding-Ochoa, Yanwen You, Pablo Martínez, Hande Karahan, Enrique Chimal-Juárez, Travis S Johnson, Jie Zhang, Susan Resnick, Jungsu Kim, Juan C Troncoso, Cristian A Lasagna-Reeves

Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer's progression

免疫代谢治疗靶向揭示了己糖激酶 2 剂量对小胶质细胞活化和阿尔茨海默病进展的关键依赖

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2024.114488

Juan F Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Paul B Fallen, Shweta S Puntambekar, Brad T Casali, Nur Jury-Garfe, Pablo Martinez, Cristian A Lasagna-Reeves, Gary E Landreth

Protocol for the isolation and proteomic analysis of pathological tau-seeds

病理性tau蛋白种子分离和蛋白质组学分析方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2024.103185

Pablo Martinez ，Henika Patel ，Yanwen You ，Emma H Doud ，Amber L Mosley ，Cristian A Lasagna-Reeves

发表日期：2024

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Network analysis identifies strain-dependent response to tau and tau seeding-associated genes

网络分析确定了对 tau 和 tau 播种相关基因的菌株依赖性反应

期刊:Journal of Experimental Medicine

影响因子:12.6

doi:10.1084/jem.20230180

Dominic J Acri, Yanwen You, Mason D Tate, Hande Karahan, Pablo Martinez, Brianne McCord, A Daniel Sharify, Sutha John, Byungwook Kim, Luke C Dabin, Stéphanie Philtjens, H R Sagara Wijeratne, Tyler J McCray, Daniel C Smith, Stephanie J Bissel, Bruce T Lamb, Cristian A Lasagna-Reeves, Jungsu Kim

微生物学

发表日期：2023

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TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation

TREM2 剪接异构体会产生可溶性 TREM2 物质，从而破坏长期增强作用

期刊:Genome Medicine

影响因子:10.4

doi:10.1186/s13073-023-01160-z

Miguel Moutinho, Israel Coronel, Andy P Tsai, Gonzalo Viana Di Prisco, Taylor Pennington, Brady K Atwood, Shweta S Puntambekar, Daniel C Smith, Pablo Martinez, Seonggyun Han, Younghee Lee, Cristian A Lasagna-Reeves, Bruce T Lamb, Stephanie J Bissel, Kwangsik Nho, Gary E Landreth

信号转导

发表日期：2023

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Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on α-Synuclein and Tau Aggregation

评估 N 和 O 连接吲哚三嗪对 α-突触核蛋白和 Tau 聚集的双重影响

期刊:ACS Chemical Neuroscience

影响因子:4.1

doi:10.1021/acschemneuro.3c00464

Eduardo Ramirez, Susantha K Ganegamage, Sehong Min, Henika Patel, Adedayo Ogunware, Germán Plascencia-Villa, Heba Alnakhala, Kazuma Shimanaka, Arati Tripathi, Kuang-Wei Wang, Xiongwei Zhu, Jean-Christophe Rochet, Min-Hao Kuo, Scott E Counts, George Perry, Ulf Dettmer, Cristian A Lasagna-Reeves, Jess

神经科学

发表日期：2023

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Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer's disease

淀粉样斑块微环境中小胶质细胞动力学增强和 tau 播种不足有助于阿尔茨海默病患者的认知恢复能力

期刊:

影响因子:

doi:10.1101/2023.07.27.550884

Nur Jury-Garfe, Yanwen You, Pablo Martínez, Javier Redding-Ochoa, Hande Karahan, Travis S Johnson, Jie Zhang, Jungsu Kim, Juan C Troncoso, Cristian A Lasagna-Reeves

Therapeutic targeting of immunometabolism in Alzheimer's disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression

阿尔茨海默病免疫代谢的治疗靶向性揭示了己糖激酶 2 剂量对小胶质细胞活化和疾病进展的关键依赖性

期刊:

影响因子:

doi:10.1101/2023.11.11.566270

Juan F Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Shweta S Puntambekar, Brad T Casali, Nur Jury, Pablo Martinez, Cristian A Lasagna-Reeves, Gary E Landreth

Bassoon contributes to tau-seed propagation and neurotoxicity

巴松管促进 tau 种子传播和神经毒性

期刊:Nature Neuroscience

影响因子:21.2

doi:10.1038/s41593-022-01191-6

Pablo Martinez ，Henika Patel ，Yanwen You ，Nur Jury ，Abigail Perkins ，Audrey Lee-Gosselin ，Xavier Taylor ，Yingjian You ，Gonzalo Viana Di Prisco ，Xiaoqing Huang ，Sayan Dutta ，Aruna B Wijeratne ，Javier Redding-Ochoa ，Syed Salman Shahid ，Juan F Codocedo ，Sehong Min ，Gary E Landreth ，Amber L Mosley ，Yu-Chien Wu ，David L McKinzie ，Jean-Christophe Rochet ，Jie Zhang ，Brady K Atwood ，Juan Troncoso ，Cristian A Lasagna-Reeves

毒理研究

发表日期：2022

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Loss of Inpp5d has disease-relevant and sex-specific effects on glial transcriptomes

Inpp5d 的缺失对神经胶质细胞转录组具有疾病相关和性别特异性的影响

Enhanced microglial dynamics and a paucity of tau seeding in the amyloid plaque microenvironment contribute to cognitive resilience in Alzheimer's disease

淀粉样斑块微环境中小胶质细胞动力学增强和 tau 播种不足有助于阿尔茨海默病患者的认知恢复能力

Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer's progression

免疫代谢治疗靶向揭示了己糖激酶 2 剂量对小胶质细胞活化和阿尔茨海默病进展的关键依赖

Protocol for the isolation and proteomic analysis of pathological tau-seeds

病理性tau蛋白种子分离和蛋白质组学分析方案

Network analysis identifies strain-dependent response to tau and tau seeding-associated genes

网络分析确定了对 tau 和 tau 播种相关基因的菌株依赖性反应

TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation

TREM2 剪接异构体会产生可溶性 TREM2 物质，从而破坏长期增强作用

Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on α-Synuclein and Tau Aggregation

评估 N 和 O 连接吲哚三嗪对 α-突触核蛋白和 Tau 聚集的双重影响

Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer's disease

淀粉样斑块微环境中小胶质细胞动力学增强和 tau 播种不足有助于阿尔茨海默病患者的认知恢复能力

Therapeutic targeting of immunometabolism in Alzheimer's disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression

阿尔茨海默病免疫代谢的治疗靶向性揭示了己糖激酶 2 剂量对小胶质细胞活化和疾病进展的关键依赖性

Bassoon contributes to tau-seed propagation and neurotoxicity

巴松管促进 tau 种子传播和神经毒性