The interplay between FOXO3 and FOXM1 influences sensitivity to AKT inhibition in PIK3CA and PIK3CA/PTEN altered estrogen receptor positive breast cancer.
FOXO3 和 FOXM1 之间的相互作用会影响 PIK3CA 和 PIK3CA/PTEN 改变的雌激素受体阳性乳腺癌对 AKT 抑制的敏感性
期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-025-00752-9
Cutano Valentina, Chia Ming Li, Wigmore Eleanor M, Hopcroft Lorna, Williamson Stuart C, Christie Amanda L, Willis Brandon, Kerr James, Ashforth Jenny, Fox Rhys, D'Arcy Sophie, Bradshaw Lauren, Blaker Catherine, Eberlein Cath, Montava-Garriga Lambert, de Bruin Elza C, Critchlow Susan E, Brindle Kevin M, Barry Simon T, Ros Susana