日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Insights into the complexity of SARS-CoV-2 M(pro) inhibition: Ebselen and its derivatives impair dimerisation of the enzyme

对SARS-CoV-2 M(pro)抑制机制复杂性的深入研究：依布硒仑及其衍生物会损害该酶的二聚化。

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2604232
Fabbian, Simone; Fabi, Silvia; Schwarz, Laurin; Preto, Giovanni; Schiavinato, Chiara; Salata, Cristiano; Crocetti, Letizia; Battistutta, Roberto; Gatto, Barbara; Sosic, Alice
SARS-CoV-2
发表日期：2026
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Discovery of Potent PDE4 Inhibitors with 3(2H)-Pyridazinone Scaffold: Synthesis, In Silico Studies and In Vitro/Vivo Evaluation

发现具有3(2H)-哒嗪酮骨架的高效PDE4抑制剂：合成、计算机模拟研究和体外/体内评价

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules31040699
Vergelli, Claudia; Crocetti, Letizia; Guerrini, Gabriella; Melani, Fabrizio; Gracia, Jordi; Buil, Maria Antonia; Garrido, Yolanda; Pagès, Lluis; Taltavull, Joan; Gavaldà, Amadeu; Calama, Elena; Giovannoni, Maria Paola
发表日期：2026
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Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease

嘌呤能信号异常是常染色体显性多囊肾病中肾囊肿形成的原因之一。

期刊:Purinergic Signalling
影响因子:2.4
doi:10.1007/s11302-025-10127-1
Ivanov, Veniamin; Wu, Andrew; Crocetti, Letizia; Meng, Ze; Shrestha-Maskey, Puja; Liao, Tang-Dong; Adrianto, Indra; Guerrini, Gabriella; Ortiz, Pablo A; Pavlov, Tengis S
信号转导
发表日期：2026
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Synthesis of 3-Carboxy-6-sulfamoylquinolones and Mefloquine-Based Compounds as Panx1 Blockers: Molecular Docking, Electrophysiological and Cell Culture Studies

3-羧基-6-氨磺酰喹诺酮类化合物和甲氟喹类化合物作为Panx1阻滞剂的合成：分子对接、电生理和细胞培养研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30102171
Crocetti, Letizia; Giovannoni, Maria Paola; Pavlov, Tengis S; Ivanov, Veniamin; Melani, Fabrizio; Guerrini, Gabriella
细胞生物学
Cell Culture
发表日期：2025
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Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines

吡唑并[1,5-a]喹唑啉的抗炎活性

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules29112421
Crocetti, Letizia; Khlebnikov, Andrei I; Guerrini, Gabriella; Schepetkin, Igor A; Melani, Fabrizio; Giovannoni, Maria Paola; Quinn, Mark T
发表日期：2024
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Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis

新型N-甲酰肽受体（FPRs）调节剂AMC3在类风湿性关节炎实验模型中的保护和镇痛作用

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox12061207
Ferrara, Valentina; Toti, Alessandra; Lucarini, Elena; Parisio, Carmen; Micheli, Laura; Ciampi, Clara; Margiotta, Francesco; Crocetti, Letizia; Vergelli, Claudia; Giovannoni, Maria Paola; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla
信号转导
关节炎
发表日期：2023
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Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers

新型喹啉类Panx-1通道阻滞剂的设计、合成及药理学评价

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24032022
Crocetti, Letizia; Giovannoni, Maria Paola; Guerrini, Gabriella; Lamanna, Silvia; Melani, Fabrizio; Bartolucci, Gianluca; Pallecchi, Marco; Paoli, Paola; Lippi, Martina; Wang, Junjie; Dahl, Gerhard
发表日期：2023
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PDE4 Inhibitors: Profiling Hits through the Multitude of Structural Classes

PDE4抑制剂：通过多种结构类别筛选先导化合物

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241411518
Jin, Jian; Mazzacuva, Francesca; Crocetti, Letizia; Giovannoni, Maria Paola; Cilibrizzi, Agostino
发表日期：2023
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Steered Molecular Dynamics Simulations Study on FABP4 Inhibitors

FABP4抑制剂的定向分子动力学模拟研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28062731
Tomarchio, Rosario; Patamia, Vincenzo; Zagni, Chiara; Crocetti, Letizia; Cilibrizzi, Agostino; Floresta, Giuseppe; Rescifina, Antonio
FABP4
发表日期：2023
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4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABA(A) Receptor Subtype

4,5-二氢-5-氧代-吡唑并[1,5-a]噻吩并[2,3-c]嘧啶：一种新型含噻吩环的骨架。化学反应性和计算机模拟研究预测其对GABA(A)受体亚型的亲和力。

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28073054
Crocetti, Letizia; Guerrini, Gabriella; Melani, Fabrizio; Vergelli, Claudia; Giovannoni, Maria Paola
信号转导
发表日期：2023
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