Spike conformational tuning rather than epitope erosion drives SARS-CoV-2 resistance to broadly neutralizing antibodies
SARS-CoV-2 对广谱中和抗体的耐药性是由刺突蛋白构象调整而非表位侵蚀驱动的。
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doi:10.21203/rs.3.rs-9365657/v1
Mohammed, Hisham; Mills, Gordon; Doe, Aaron; Ors, Aysegul; Cros, Hugo; Sevim, Selim; Lee, Jinho; Creason, Allison; Zangirolani, Gabriel; Rose, Joshua; Youm, Isaac; Ozmen, Furkan; Ozmen, Tugba; Dane, Mark; Scott, Willam; Chang, Matthew; Chin, Koei; Heiser, Laura; Stommel, Jayne; Fagerlund, Riku; Uğurlu, Hasan; Salminen, Petja; Žusinaite, Eva; Mäkelä, Anna R; Kesti, Tapio; Merits, Andres; Rissanen, Ilona; Saksela, Kalle
