日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.

miR-1-5p 靶向 TGF-βR1,在患有肺动脉高压的大鼠肥大心脏中受到抑制

Connolly Martin, Garfield Benjamin E, Crosby Alexi, Morrell Nick W, Wort Stephen J, Kemp Paul R

Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension.

利用 PTC124 靶向 BMPR2 中过早终止突变的翻译通读,治疗肺动脉高压

Long Lu, Yang Xudong, Southwood Mark, Moore Stephen, Crosby Alexi, Upton Paul D, Dunmore Benjamin J, Morrell Nicholas W

Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension

生长/分化因子15导致肺动脉高压患者出现TGFβ激活激酶1依赖性肌肉萎缩

Garfield, Benjamin E; Crosby, Alexi; Shao, Dongmin; Yang, Peiran; Read, Cai; Sawiak, Steven; Moore, Stephen; Parfitt, Lisa; Harries, Carl; Rice, Martin; Paul, Richard; Ormiston, Mark L; Morrell, Nicholas W; Polkey, Michael I; Wort, Stephen John; Kemp, Paul R

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice

造血干细胞移植改变了Bmpr2缺陷小鼠对肺动脉高压的易感性

Crosby, Alexi; Toshner, Mark R; Southwood, Mark R; Soon, Elaine; Dunmore, Benjamin J; Groves, Emily; Moore, Stephen; Wright, Penny; Ottersbach, Katrin; Bennett, Cavan; Guerrero, Jose; Ghevaert, Cedric; Morrell, Nicholas W

miR-322-5p targets IGF-1 and is suppressed in the heart of rats with pulmonary hypertension

miR-322-5p靶向IGF-1,并在肺动脉高压大鼠心脏中表达受到抑制。

Connolly, Martin; Garfield, Benjamin E; Crosby, Alexi; Morrell, Nick W; Wort, Stephen J; Kemp, Paul R

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension

骨形态发生蛋白受体II型缺乏和炎症细胞因子生成增加,是导致肺动脉高压的途径。

Soon, Elaine; Crosby, Alexi; Southwood, Mark; Yang, Peiran; Tajsic, Tamara; Toshner, Mark; Appleby, Sarah; Shanahan, Catherine M; Bloch, Kenneth D; Pepke-Zaba, Joanna; Upton, Paul; Morrell, Nicholas W

Hepatic Shunting of Eggs and Pulmonary Vascular Remodeling in Bmpr2(+/-) Mice with Schistosomiasis

血吸虫病Bmpr2(+/-)小鼠的肝脏虫卵分流和肺血管重塑

Crosby, Alexi; Soon, Elaine; Jones, Frances M; Southwood, Mark R; Haghighat, Leila; Toshner, Mark R; Raine, Tim; Horan, Ian; Yang, Peiran; Moore, Stephen; Ferrer, Elisabet; Wright, Penny; Ormiston, Mark L; White, R James; Haight, Deborah A; Dunne, David W; Morrell, Nicholas W

Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline

激活素样激酶5 (ALK5) 介导家族性肺动脉高压患者血管平滑肌细胞的异常增殖,并参与单克罗他林诱导的实验性肺动脉高压的进展。

Thomas, Matthew; Docx, Cerys; Holmes, Alan M; Beach, Sarah; Duggan, Nicholas; England, Karen; Leblanc, Catherine; Lebret, Clemence; Schindler, Francis; Raza, Farheen; Walker, Christoph; Crosby, Alexi; Davies, Rachel J; Morrell, Nicholas W; Budd, David C

Lack of involvement of the autonomic nervous system in early ventilatory and pulmonary vascular acclimatization to hypoxia in humans

人类早期呼吸和肺血管对低氧的适应过程中,自主神经系统参与不足。

Liu, Chun; Smith, Thomas G; Balanos, George M; Brooks, Jerome; Crosby, Alexi; Herigstad, Mari; Dorrington, Keith L; Robbins, Peter A