日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of charge mutations in solvent exposed Lys residues of superoxide dismutase 1 do not induce inclusion formation in cultured cell models

超氧化物歧化酶 1 中暴露于溶剂的赖氨酸残基的电荷丢失突变不会在培养细胞模型中诱导包涵体形成。

Crosby, Keith; Crown, Anthony M; Roberts, Brittany L; Brown, Hilda; Ayers, Jacob I; Borchelt, David R

Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice

新生小鼠注射AAV后,脊髓和大脑中AAV广泛且高效转导,并可能对ALS小鼠产生疾病改善作用。

Ayers, Jacob I; Fromholt, Susan; Sinyavskaya, Olga; Siemienski, Zoe; Rosario, Awilda M; Li, Andrew; Crosby, Keith W; Cruz, Pedro E; DiNunno, Nadia M; Janus, Christopher; Ceballos-Diaz, Carolina; Borchelt, David R; Golde, Todd E; Chakrabarty, Paramita; Levites, Yona

Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation

显著提高SOD1突变小鼠脊髓运动神经元中αB-晶状体蛋白的水平并不能显著延缓瘫痪的发生或减弱突变蛋白的聚集。

Xu, Guilian; Fromholt, Susan; Ayers, Jacob I; Brown, Hilda; Siemienski, Zoe; Crosby, Keith W; Mayer, Christopher A; Janus, Christopher; Borchelt, David R

Cross-laboratory validation of the OncoScan® FFPE Assay, a multiplex tool for whole genome tumour profiling

OncoScan® FFPE 检测(一种用于全基因组肿瘤分析的多重检测工具)的跨实验室验证

Foster, Joseph M; Oumie, Assa; Togneri, Fiona S; Vasques, Fabiana Ramos; Hau, Debra; Taylor, Morag; Tinkler-Hundal, Emma; Southward, Katie; Medlow, Paul; McGreeghan-Crosby, Keith; Halfpenny, Iris; McMullan, Dominic J; Quirke, Phil; Keating, Katherine E; Griffiths, Mike; Spink, Karen G; Brew, Fiona

Features of wild-type human SOD1 limit interactions with misfolded aggregates of mouse G86R Sod1.

野生型人类 SOD1 的特征限制了其与小鼠 G86R Sod1 错误折叠聚集体的相互作用

Qualls David A, Prudencio Mercedes, Roberts Brittany L T, Crosby Keith, Brown Hilda, Borchelt David R

Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain

衣壳血清型和注射时间决定了新生小鼠脑内AAV的转导效率

Chakrabarty, Paramita; Rosario, Awilda; Cruz, Pedro; Siemienski, Zoe; Ceballos-Diaz, Carolina; Crosby, Keith; Jansen, Karen; Borchelt, David R; Kim, Ji-Yoen; Jankowsky, Joanna L; Golde, Todd E; Levites, Yona