日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CREB depletion in smooth muscle cells promotes medial thickening, adventitial fibrosis and elicits pulmonary hypertension

平滑肌细胞中 CREB 的缺失会促进血管中层增厚、外膜纤维化,并引发肺动脉高压。

Garat, Chrystelle V; Majka, Susan M; Sullivan, Timothy M; Crossno, Joseph T Jr; Reusch, Jane E B; Klemm, Dwight J

Obesity-related pulmonary arterial hypertension in rats correlates with increased circulating inflammatory cytokines and lipids and with oxidant damage in the arterial wall but not with hypoxia.

大鼠肥胖相关的肺动脉高压与循环炎症细胞因子和脂质增加以及动脉壁氧化损伤相关,但与缺氧无关

Irwin David C, Garat Chrystelle V, Crossno Joseph T Jr, MacLean Paul S, Sullivan Timothy M, Erickson Paul F, Jackman Matthew R, Harral Julie W, Reusch Jane E B, Klemm Dwight J

Reduction of reactive oxygen species prevents hypoxia-induced CREB depletion in pulmonary artery smooth muscle cells

活性氧的减少可预防肺动脉平滑肌细胞中缺氧诱导的CREB耗竭。

Klemm, Dwight J; Majka, Susan M; Crossno, Joseph T Jr; Psilas, John C; Reusch, Jane E B; Garat, Chrystelle V