日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model

恩格列净可提高代谢效率并改善肥厚型心肌病小鼠模型中的左心室肥厚。

期刊:European Heart Journal
影响因子:35.6
doi:10.1093/eurheartj/ehaf324
Baka, Tomas; Moore, Jarrod; Qin, Fuzhong; Yurista, Salva R; Zhang, Aifeng; He, Huamei; Chambers, Jordan M; Croteau, Dominique; Goel, Raghuveera K; Smith, Hunter; Wang, Miranda C; Chen, Christopher S; Hobai, Ion A; Rombaldova, Martina; Kuda, Ondrej; Tardiff, Jil C; Balschi, James A; Pimentel, David R; Seidman, Christine E; Seidman, Jonathan G; Emili, Andrew; Colucci, Wilson S; Luptak, Ivan
心血管
心肌病
代谢
发表日期：2025
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SGLT2 inhibitor upregulates myocardial genes for oxidative phosphorylation and fatty acid metabolism in Gαq-mice.

SGLT2 抑制剂可上调 Gαq 小鼠心肌氧化磷酸化和脂肪酸代谢相关基因

期刊:Journal of Molecular and Cellular Cardiology Plus
影响因子:2.2
doi:10.1016/j.jmccpl.2025.100296
Chambers Jordan M, Croteau Dominique, Pimentel David R, Gower Adam C, Panagia Marcello, Baka Tomas, Qin Fuzhong, Luptak Ivan, Colucci Wilson S
代谢
磷酸化
发表日期：2025
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SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy

SGLT2抑制剂艾格列净可降低升高的细胞内钠浓度，并改善糖尿病心肌病患者的能量代谢和收缩功能。

期刊:Biomedicine & Pharmacotherapy
影响因子:7.5
doi:10.1016/j.biopha.2023.114310
Croteau, Dominique; Baka, Tomas; Young, Sara; He, Huamei; Chambers, Jordan M; Qin, Fuzhong; Panagia, Marcello; Pimentel, David R; Balschi, James A; Colucci, Wilson S; Luptak, Ivan
SGLT2
心肌病
心血管
代谢
糖尿病
细胞生物学
发表日期：2023
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Effects of Sodium-Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice

埃格列净抑制钠-葡萄糖协同转运蛋白2对糖尿病小鼠线粒体功能、能量代谢和代谢基因表达的影响

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.120.019995
Croteau, Dominique; Luptak, Ivan; Chambers, Jordan M; Hobai, Ion; Panagia, Marcello; Pimentel, David R; Siwik, Deborah A; Qin, Fuzhong; Colucci, Wilson S
糖尿病
线粒体
代谢
发表日期：2021
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Redox-Resistant SERCA [Sarco(endo)plasmic Reticulum Calcium ATPase] Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload-Induced Myocardial Failure in Mice

抗氧化还原SERCA [肌浆网（内质网）钙ATP酶]可减弱氧化剂刺激的心肌细胞线粒体钙和细胞凋亡，并减轻小鼠压力超负荷诱导的心肌衰竭

期刊:Circulation
影响因子:38.6
doi:10.1161/CIRCULATIONAHA.120.048183
Goodman, Jena B; Qin, Fuzhong; Morgan, Robert J; Chambers, Jordan M; Croteau, Dominique; Siwik, Deborah A; Hobai, Ion; Panagia, Marcello; Luptak, Ivan; Bachschmid, Markus; Tong, XiaoYong; Pimentel, David R; Cohen, Richard A; Colucci, Wilson S
凋亡
表观遗传
Apoptosis
线粒体
细胞生物学
发表日期：2020
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Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation

通过谷胱甘肽还原酶-1和蛋白质S-谷胱甘肽化进行氧化还原调控

期刊:Antioxidants & Redox Signaling
影响因子:6.1
doi:10.1089/ars.2019.7963
Matsui, Reiko; Ferran, Beatriz; Oh, Albin; Croteau, Dominique; Shao, Di; Han, Jingyan; Pimentel, David Richard; Bachschmid, Markus Michael
信号转导
发表日期：2020
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Doxycycline decreases amyloidogenic light chain-induced autophagy in isolated primary cardiac myocytes

强力霉素可降低分离的原代心肌细胞中淀粉样蛋白轻链诱导的自噬

期刊:International Journal of Cardiology
影响因子:3.2
doi:10.1016/j.ijcard.2020.07.016
Valero-Muñoz, María; Wilson, Richard M; Bretón-Romero, Rosa; Croteau, Dominique; Seldin, David C; Sam, Flora
细胞生物学
自噬
发表日期：2020
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Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease

丁酸盐增加线粒体ATP合成可使代谢性心脏病患者的ADP水平和收缩功能恢复正常。

期刊:NMR in Biomedicine
影响因子:2.7
doi:10.1002/nbm.4258
Panagia, Marcello; He, Huamei; Baka, Tomas; Pimentel, David R; Croteau, Dominique; Bachschmid, Markus M; Balschi, James A; Colucci, Wilson S; Luptak, Ivan
心脏病
线粒体
心血管
代谢
发表日期：2020
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Genetically targeted fluorescent probes reveal dynamic calcium responses to adrenergic signaling in multiple cardiomyocyte compartments

基因靶向荧光探针揭示了心肌细胞多个区室中肾上腺素能信号传导引起的动态钙反应

期刊:International Journal of Biochemistry & Cell Biology
影响因子:2.8
doi:10.1016/j.biocel.2019.105569
Luptak, Ivan; Morgan, Robert; Baka, Tomas; Croteau, Dominique; Moverman, Daniel; Sarnak, Hannah; Kirber, Michael; Bachschmid, Markus M; Colucci, Wilson S; Pimentel, David R
信号转导
细胞生物学
IF
免疫/内分泌
发表日期：2019
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Multiplexed Optical Imaging of Energy Substrates Reveals That Left Ventricular Hypertrophy Is Associated With Brown Adipose Tissue Activation

多重光学成像技术揭示左心室肥厚与棕色脂肪组织活化相关

期刊:Circulation-Cardiovascular Imaging
影响因子:7
doi:10.1161/CIRCIMAGING.117.007007
Panagia, Marcello; Chen, Howard H; Croteau, Dominique; Iris Chen, Yin-Ching; Ran, Chongzhao; Luptak, Ivan; Josephson, Lee; Colucci, Wilson S; Sosnovik, David E
发表日期：2018
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