日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of VU0467319: an M(1) Positive Allosteric Modulator Candidate That Advanced into Clinical Trials

VU0467319 的发现:一种进入临床试验的 M(1) 正向变构调节剂候选药物

Poslunsey, Michael S; Wood, Michael R; Han, Changho; Stauffer, Shaun R; Panarese, Joseph D; Melancon, Bruce J; Engers, Julie L; Dickerson, Jonathan W; Peng, Weimin; Noetzel, Meredith J; Cho, Hyekyung P; Rodriguez, Alice L; Hopkins, Corey R; Morrison, Ryan; Crouch, Rachel D; Bridges, Thomas M; Blobaum, Anna L; Boutaud, Olivier; Daniels, J Scott; Kates, Michael J; Castelhano, Arlindo; Rook, Jerri M; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W

Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions

某些非P450人类氧化还原酶在化学物质的保护和毒性作用中的作用:反应综述与汇编

Rendić, Slobodan P; Crouch, Rachel D; Guengerich, F Peter

Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CL(pro))

基于结构的ML300衍生非共价抑制剂靶向严重急性呼吸综合征冠状病毒3CL蛋白酶(SARS-CoV-2 3CL(pro))的优化

Han, Sang Hoon; Goins, Christopher M; Arya, Tarun; Shin, Woo-Jin; Maw, Joshua; Hooper, Alice; Sonawane, Dhiraj P; Porter, Matthew R; Bannister, Breyanne E; Crouch, Rachel D; Lindsey, A Abigail; Lakatos, Gabriella; Martinez, Steven R; Alvarado, Joseph; Akers, Wendell S; Wang, Nancy S; Jung, Jae U; Macdonald, Jonathan D; Stauffer, Shaun R

Bioactivation and reactivity research advances - 2021 year in review

生物活化和反应性研究进展——2021年回顾

Jackson, Klarissa D; Argikar, Upendra A; Cho, Sungjoon; Crouch, Rachel D; Driscoll, James P; Heck, Carley J S; King, Lloyd; Maw, Hlaing Holly; Miller, Grover P; Seneviratne, Herana Kamal; Wang, Shuai; Wei, Cong; Zhang, Donglu; Khojasteh, S Cyrus

Case Study 11: Considerations for Enzyme Mapping Experiments-Interaction Between the Aldehyde Oxidase Inhibitor Hydralazine and Glutathione

案例研究 11:酶图谱实验的注意事项——醛氧化酶抑制剂肼屈嗪与谷胱甘肽的相互作用

Crouch, Rachel D; Beers, Jessica L; Jackson, Klarissa D

Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation

CYP3A活性个体差异影响拉帕替尼的生物活化

Bissada, Jennifer E; Truong, Vivian; Abouda, Arsany A; Wines, Kahari J; Crouch, Rachel D; Jackson, Klarissa D

A novel in vitro allometric scaling methodology for aldehyde oxidase substrates to enable selection of appropriate species for traditional allometry.

一种新型的醛氧化酶底物体外异速生长标度方法,可用于选择适合传统异速生长的物种

Crouch Rachel D, Hutzler J Matthew, Daniels J Scott