日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inflammasome activation links enteric Salmonella Typhimurium infection to a rapid, cytokine-dependent increase in intestinal mucin release

炎症小体激活将肠道鼠伤寒沙门氏菌感染与肠道黏蛋白释放的快速、细胞因子依赖性增加联系起来

Han, Xiao; Allaire, Joannie M; Crowley, Shauna M; Chan, Jocelyn J; Lau, Kelly; Zhang, Conghao; Hirota, Simon A; Bergstrom, Kirk; Knodler, Leigh A; Vallance, Bruce A

Intestinal restriction of Salmonella Typhimurium requires caspase-1 and caspase-11 epithelial intrinsic inflammasomes

沙门氏菌在肠道中的限制需要 caspase-1 和 caspase-11 上皮固有炎症小体。

Crowley, Shauna M; Han, Xiao; Allaire, Joannie M; Stahl, Martin; Rauch, Isabella; Knodler, Leigh A; Vallance, Bruce A

Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes.

沙门氏菌感染小鼠和人类肠类器官衍生的单层细胞可引起上皮固有炎症小体的差异性激活

Holly Mayumi K, Han Xiao, Zhao Edward J, Crowley Shauna M, Allaire Joannie M, Knodler Leigh A, Vallance Bruce A, Smith Jason G

Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen

磷酸化碳水化合物的主动转运促进细菌病原体的肠道定植和传播

Sit, Brandon; Crowley, Shauna M; Bhullar, Kirandeep; Lai, Christine Chieh-Lin; Tang, Calvin; Hooda, Yogesh; Calmettes, Charles; Khambati, Husain; Ma, Caixia; Brumell, John H; Schryvers, Anthony B; Vallance, Bruce A; Moraes, Trevor F

Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens

非经典炎症小体激活caspase-4/caspase-11介导上皮细胞对肠道细菌病原体的防御

Knodler, Leigh A; Crowley, Shauna M; Sham, Ho Pan; Yang, Hyungjun; Wrande, Marie; Ma, Caixia; Ernst, Robert K; Steele-Mortimer, Olivia; Celli, Jean; Vallance, Bruce A

A novel mouse model of Campylobacter jejuni gastroenteritis reveals key pro-inflammatory and tissue protective roles for Toll-like receptor signaling during infection

一种新型的空肠弯曲菌胃肠炎小鼠模型揭示了Toll样受体信号通路在感染过程中发挥的关键促炎和组织保护作用。

Stahl, Martin; Ries, Jenna; Vermeulen, Jenny; Yang, Hong; Sham, Ho Pan; Crowley, Shauna M; Badayeva, Yuliya; Turvey, Stuart E; Gaynor, Erin C; Li, Xiaoxia; Vallance, Bruce A

Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses

肠道上皮特异性MyD88信号通路通过促进保护性杯状细胞和抗菌反应,影响宿主对感染性结肠炎的易感性。

Bhinder, Ganive; Stahl, Martin; Sham, Ho Pan; Crowley, Shauna M; Morampudi, Vijay; Dalwadi, Udit; Ma, Caixia; Jacobson, Kevan; Vallance, Bruce A