Crux相关文献与解析，生知库 | 链接生命科学的每一步

Rationale and design of the POLEM trial: avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III mismatch repair deficient or POLE exonuclease domain mutant colon cancer: a phase III randomised study

POLEM试验的原理和设计：avelumab联合氟尿嘧啶类化疗作为III期错配修复缺陷或POLE外切酶结构域突变结肠癌的辅助治疗：一项III期随机研究

doi:10.1136/esmoopen-2019-000638

Lau, David; Kalaitzaki, Eleftheria; Church, David N; Pandha, Hardev; Tomlinson, Ian; Annels, Nicola; Gerlinger, Marco; Sclafani, Francesco; Smith, Gillian; Begum, Ruwaida; Crux, Richard; Gillbanks, Angela; Wordsworth, Sarah; Chau, Ian; Starling, Naureen; Cunningham, David; Dhillon, Tony

In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria

星形胶质细胞微区体内 Ca2+ 成像揭示了淀粉样蛋白前体对线粒体的关键作用

期刊:Glia

影响因子:5.4

doi:10.1002/glia.23584

Elena Montagna, Sophie Crux, Manja Luckner, Julia Herber, Alessio V Colombo, Petar Marinković, Sabina Tahirovic, Stefan F Lichtenthaler, Gerhard Wanner, Ulrike C Müller, Carmelo Sgobio, Jochen Herms

TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro

TrpV1受体激活可挽救Aβ诱导的小鼠海马损伤引起的神经元功能和网络伽马振荡

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.37703

Hugo Balleza-Tapia, Sophie Crux, Yuniesky Andrade-Talavera, Pablo Dolz-Gaiton, Daniela Papadia, Gefei Chen, Jan Johansson, André Fisahn

Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections?

人类白细胞抗原 (HLA) 与免疫调节：经典和非经典 HLA 等位基因如何调节对人类免疫缺陷病毒和丙型肝炎病毒感染的免疫反应？

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2017.00832

Crux, Nicole B; Elahi, Shokrollah

Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling

阿托伐他汀通过靶向Ras激活的mTOR信号通路来下调共抑制受体的表达。

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.21003

Okoye, Isobel; Namdar, Afshin; Xu, Lai; Crux, Nicole; Elahi, Shokrollah

mTOR

发表日期：2017

文献求助收藏

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis

淀粉样前体蛋白通过调节D-丝氨酸稳态来维持成年大脑树突棘的组成性和适应性可塑性。

期刊:EMBO Journal

影响因子:8.3

doi:10.15252/embj.201694085

Zou, Chengyu; Crux, Sophie; Marinesco, Stephane; Montagna, Elena; Sgobio, Carmelo; Shi, Yuan; Shi, Song; Zhu, Kaichuan; Dorostkar, Mario M; Müller, Ulrike C; Herms, Jochen

神经科学

发表日期：2016

文献求助收藏

Objective detection of visual field defects with multifrequency VEPs

利用多频视觉诱发电位客观检测视野缺损

Rationale and design of the POLEM trial: avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III mismatch repair deficient or POLE exonuclease domain mutant colon cancer: a phase III randomised study

POLEM试验的原理和设计：avelumab联合氟尿嘧啶类化疗作为III期错配修复缺陷或POLE外切酶结构域突变结肠癌的辅助治疗：一项III期随机研究

In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria

星形胶质细胞微区体内 Ca2+ 成像揭示了淀粉样蛋白前体对线粒体的关键作用

TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro

TrpV1受体激活可挽救Aβ诱导的小鼠海马损伤引起的神经元功能和网络伽马振荡

Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections?

人类白细胞抗原 (HLA) 与免疫调节：经典和非经典 HLA 等位基因如何调节对人类免疫缺陷病毒和丙型肝炎病毒感染的免疫反应？

Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling

阿托伐他汀通过靶向Ras激活的mTOR信号通路来下调共抑制受体的表达。

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis

淀粉样前体蛋白通过调节D-丝氨酸稳态来维持成年大脑树突棘的组成性和适应性可塑性。