日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV.

代谢工程通过改变细胞外囊泡包裹的 AAV 的脂质组成来提高转导效率和下游载体分离

Espinoza Paula, Cheng Ming, Ng Carrie, Cruz Demitri de la, Wasson Elizabeth D, McCarthy Deirdre M, Bhide Pradeep G, Maguire Casey A, Santoscoy Miguel C

Probing aspects of extracellular vesicle associated AAV allows increased vector yield and insight into its transduction and immune-evasive properties.

探究与细胞外囊泡相关的 AAV 的各个方面,可以提高载体产量,并深入了解其转导和免疫逃避特性

Cheng Ming, Cruz Demitri de la, Crain Adam V, Espinoza Paula, Ng Carrie, Elmore Zachary C, Asokan Aravind, Maguire Casey A