日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolomic profiling of patients with lupus nephritis reveals unique metabolites that are modulated through type I interferon inhibition by anifrolumab treatment in a phase 2 trial

在一项二期临床试验中,对狼疮性肾炎患者进行代谢组学分析发现,阿尼弗鲁单抗治疗可通过抑制I型干扰素来调节独特的代谢物。

Gavin, Patrick G; Allman, Erik L; Jayne, David; Mysler, Eduardo; Amoura, Zahir; Di Poto, Cristina; Tian, Xiang; Hess, Sonja; Csomor, Eszter; Brohawn, Philip Z; Muthas, Daniel; Platt, Adam; Anzillotti, Consuelo; Stone, Heena; Seth, Asha; Woollard, Kevin; Al-Mossawi, Hussein; Lindholm, Catharina; Ferrari, Nicola

Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of two phase 3 trials

在两项 3 期临床试验中,基因表达和蛋白质组学分析表明,使用阿尼弗鲁单抗阻断 I 型干扰素可调节系统性红斑狼疮患者的关键免疫病理通路。

Baker, Tina; Sharifian, Hoda; Newcombe, Paul J; Gavin, Patrick G; Lazarus, Mark N; Ramaswamy, Madhu; White, Wendy I; Ferrari, Nicola; Muthas, Daniel; Tummala, Raj; Morand, Eric F; Furie, Richard A; Vital, Edward M; Chamberlain, Chris; Platt, Adam; Al-Mossawi, Hussein; Brohawn, Philip Z; Csomor, Eszter

Epithelial Interleukin-1 Receptor-Like-1 Activation Is Contingent on Interleukin-33 Isoforms and Asthma-Related Receptor Variation.

上皮细胞白细胞介素-1受体样-1的激活取决于白细胞介素-33同工型和哮喘相关受体变异

Portelli Michael A, Ketelaar Maria E, Bates Stewart, Csomor Eszter, Shaw Dominick, Emsley Jonas, Brightling Christopher, Hall Ian, Affleck Karen, Edwards Matthew, Nawijn Martijn C, Koppelman Gerard H, Van Oosterhout Antoon J, Sayers Ian

Integrated analysis of dermal blister fluid proteomics and genome-wide skin gene expression in systemic sclerosis: an observational study

系统性硬化症患者皮肤水疱液蛋白质组学与全基因组皮肤基因表达的综合分析:一项观察性研究

Clark, Kristina E N; Csomor, Eszter; Campochiaro, Corrado; Galwey, Nicholas; Nevin, Katherine; Morse, Mary A; Teo, Yee Voan; Freudenberg, Johannes; Ong, Voon H; Derrett-Smith, Emma; Wisniacki, Nicolas; Flint, Shaun M; Denton, Christopher P

Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis

一项针对系统性硬化症的抗抑癌素M单克隆抗体的随机II期研究提供的生物学和临床见解

Denton, Christopher P; Del Galdo, Francesco; Khanna, Dinesh; Vonk, Madelon C; Chung, Lorinda; Johnson, Sindhu R; Varga, John; Furst, Daniel E; Temple, Jane; Zecchin, Chiara; Csomor, Eszter; Lee, Amy; Wisniacki, Nicolas; Flint, Shaun M; Reid, Juliet