Pharmacology and macrophage modulation of HPGDS inhibitor PK007 demonstrate reduced disease severity in DMD-affected muscles of the mdx mouse model.
HPGDS抑制剂PK007的药理学和巨噬细胞调节作用表明,在mdx小鼠模型中,DMD受影响的肌肉的疾病严重程度有所降低
期刊:Skeletal Muscle
影响因子:4.4
doi:10.1186/s13395-025-00379-1
Yarlagadda Sai, Sheremeta Chynna-Loren, Cheung Sang Won, Cuffe Alison, Grounds Miranda D, Smythe Mark L, Noakes Peter G