Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement
CREBBP突变淋巴瘤中CD40反应性增强子激活减弱可通过强制CD4 T细胞参与来恢复。
期刊:Blood
影响因子:23.1
doi:10.1182/blood.2024026664
Yang, Haopeng; Zhang, Wenchao; Ravanmehr, Vida; Cui, Guiling; Bowman, Kevin; Chen, Ruidong; Henderson, Jared M; Lockman, Shyanne; Rojas, Estela; Wilson, Ashley; Parsons, Sydney; Mechaly, Ariel; Regad, Leslie; Haouz, Ahmed; Flowers, Christopher R; Neelapu, Sattva; Nastoupil, Loretta; Davis, R Eric; Deng, Qing; Rodrigues-Lima, Fernando; Green, Michael R
T细胞
淋巴瘤
CD40
CREB
T细胞
细胞生物学
CD4
免疫/内分泌