文献库，生知库 | 链接生命科学的每一步

日期影响因子

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

胆固醇通过稳定 EGFR 蛋白促进肺腺癌脑转移，进而驱动 EMT、代谢重编程和转移前微环境形成

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.73843

Chen, Ying; Cui, Xiaoteng; Shi, Xinyi; Yang, Xu; Cao, Yujing; Li, Haolin; Zhan, Qi; Wang, Qixue; Li, Ang; Cheng, Qihong; Wang, Yunfei; Zhou, Junhu; Wang, MingJie; Kang, Chunsheng; Liu, Xiaomin

代谢重编程

发表日期：2026

文献求助收藏

VITA-GBM: EPIC-0502-driven HIF1α degradation overcomes bevacizumab resistance and synergizes with TMZ in glioblastoma

VITA-GBM：EPIC-0502 驱动的 HIF1α 降解克服了贝伐珠单抗耐药性，并与替莫唑胺在胶质母细胞瘤中产生协同作用

期刊:Neuro-Oncology

影响因子:13.4

doi:10.1093/neuonc/noaf293

Ding, Yaqing; Zhan, Qi; Cui, Longtao; Cui, Xiaoteng; Zhao, Yilin; Wang, Qixue; Hong, Biao; Huang, Yanping; Su, Dongyuan; Cheng, Chunchao; Xu, Hanyi; Liang, Siwen; Zhao, Xun; Liu, Yuhao; Kang, Chunsheng

细胞生物学

发表日期：2026

文献求助收藏

PEAKS activation by PROTAC EPIC-0726 potentiates temozolomide in glioblastoma via K63/K48 ubiquitination-dependent ERK/AKT suppression and p21 stabilization

PROTAC EPIC-0726 通过 K63/K48 泛素化依赖的 ERK/AKT 抑制和 p21 稳定增强 PEAKS 激活，从而增强替莫唑胺在胶质母细胞瘤中的疗效。

期刊:Neuro-Oncology

影响因子:13.4

doi:10.1093/neuonc/noaf253

Hong, Biao; Su, Dongyuan; Cui, Xiaoteng; Zhao, Jixing; Wang, Qixue; Zhan, Qi; Yang, Eryan; Yang, Shixue; Ju, Jiasheng; Huang, Yanping; Cheng, Chunchao; Ding, Yaqing; Xu, Hanyi; Cui, Longtao; Zhao, Yilin; Zhao, Xun; Liang, Siwen; Liu, Yuhao; Kang, Chunsheng

细胞生物学

发表日期：2026

文献求助收藏

LPC-engineered liposomes activate transcytosis for paclitaxel brain delivery and potentiation of TTFields/TMZ via TALECT regimen in glioblastoma

LPC工程化脂质体通过TALECT方案激活胞吞作用，将紫杉醇递送至脑部，并增强TTFields/TMZ在胶质母细胞瘤中的疗效。

期刊:Theranostics

影响因子:13.3

doi:10.7150/thno.122658

Zhan, Qi; Yi, Kaikai; Yang, Shixue; Hong, Biao; Su, Dongyuan; Zhao, Jixing; Wang, Qixue; Cui, Xiaoteng; Huang, Yanping; Ding, Yaqing; Cheng, Chunchao; Ju, Jiasheng; Kang, Chunsheng

细胞生物学

发表日期：2026

文献求助收藏

Linagliptin synergizes with cPLA2 inhibition to enhance temozolomide efficacy by interrupting DPP4-mediated EGFR stabilization in glioma.

利格列汀与 cPLA2 抑制剂协同作用，通过干扰 DPP4 介导的 EGFR 在胶质瘤中的稳定作用来增强替莫唑胺的疗效

期刊:Acta Pharmaceutica Sinica B

影响因子:14.6

doi:10.1016/j.apsb.2025.05.012

Su Dongyuan, Hong Biao, Yang Shixue, Zhao Jixing, Cui Xiaoteng, Zhan Qi, Yi Kaikai, Huang Yanping, Ju Jiasheng, Yang Eryan, Wang Qixue, Zhou Junhu, Wang Yunfei, Liu Xing, Kang Chunsheng

发表日期：2025

文献求助收藏

CYP3A5 promotes glioblastoma stemness and chemoresistance through fine-tuning NAD(+)/NADH ratio

CYP3A5 通过精细调节 NAD(+)/NADH 比值来促进胶质母细胞瘤干性和化疗耐药性。

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:12.8

doi:10.1186/s13046-024-03254-x

Hu, Wentao; Cui, Xiaoteng; Liu, Hongyu; Li, Ze; Chen, Xu; Wang, Qixue; Zhang, Guolu; Wen, Er; Lan, Jinxin; Chen, Junyi; Liu, Jialin; Kang, Chunsheng; Chen, Ling

细胞生物学

发表日期：2025

文献求助收藏

Machine learning and multi-omics analysis reveal key regulators of proneural-mesenchymal transition in glioblastoma

机器学习和多组学分析揭示胶质母细胞瘤中神经间质转化的关键调控因子

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-04862-z

Xu, Can; Yang, Jin; Xiong, Huan; Cui, Xiaoteng; Zhang, Yuhao; Gao, Mingjun; He, Lei; Fang, Qiuyue; Han, Changxi; Liu, Wei; Wang, Yangyang; Zhang, Jin; Yuan, Ying; Zeng, Zhaomu; Xu, Ruxiang

细胞生物学

发表日期：2025

文献求助收藏

HIF1α/ATF3 partake in PGK1 K191/K192 succinylation by modulating P4HA1/succinate signaling in glioblastoma

HIF1α/ATF3通过调节胶质母细胞瘤中的P4HA1/琥珀酸信号通路参与PGK1 K191/K192的琥珀酰化。

期刊:Neuro-Oncology

影响因子:13.4

doi:10.1093/neuonc/noae040

Yang, Shixue; Zhan, Qi; Su, Dongyuan; Cui, Xiaoteng; Zhao, Jixing; Wang, Qixue; Hong, Biao; Ju, Jiasheng; Cheng, Chunchao; Yang, Eryan; Kang, Chunsheng

细胞生物学

发表日期：2024

文献求助收藏

EPIC-1042 as a potent PTRF/Cavin1-caveolin-1 interaction inhibitor to induce PARP1 autophagic degradation and suppress temozolomide efflux for glioblastoma

EPIC-1042 是一种强效的 PTRF/Cavin1-caveolin-1 相互作用抑制剂，可诱导 PARP1 自噬降解并抑制替莫唑胺外排，用于治疗胶质母细胞瘤。

期刊:Neuro-Oncology

影响因子:13.4

doi:10.1093/neuonc/noad159

Hong, Biao; Yang, Eryan; Su, Dongyuan; Ju, Jiasheng; Cui, Xiaoteng; Wang, Qixue; Tong, Fei; Zhao, Jixing; Yang, Shixue; Cheng, Chunchao; Xin, Lei; Xiao, Menglin; Yi, Kaikai; Zhan, Qi; Ding, Yaqing; Xu, Hanyi; Cui, Longtao; Kang, Chunsheng

细胞生物学

发表日期：2024

文献求助收藏

Retraction Notice to: Precise editing of FGFR3-TACC3 fusion genes with CRISPR-Cas13a in glioblastoma

撤稿声明：利用 CRISPR-Cas13a 技术精确编辑胶质母细胞瘤中的 FGFR3-TACC3 融合基因

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2024.04.032

Wu, Ye; Jin, Weili; Wang, Qixue; Zhou, Junhu; Wang, Yunfei; Tan, Yanli; Cui, Xiaoteng; Tong, Fei; Yang, Eryan; Wang, Jian; Kang, Chunsheng

细胞生物学

发表日期：2024

文献求助收藏