日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting of IRAK4 and GSPT1 enhances therapeutic efficacy in AML via c-Myc destabilization.

靶向 IRAK4 和 GSPT1 可通过 c-Myc 不稳定增强 AML 的治疗效果

Vick Eric J, Hassan Aishlin, Choi Kwangmin, Bennett Joshua, Muto Tomoya, Clough Courtnee A, Culver-Cochran Ashley E, Hueneman Kathleen, Bolanos Lyndsey C, Wunderlich Mark, Zhang Xiaohu, McKnight Crystal, Ceribelli Michele, Holland David, Klumpp-Thomas Carleen, Greis Kenneth D, Thomas Craig J, Starczynowski Daniel T

IRAK1/4/pan-FLT3 Kinase Inhibitors with Reduced hERG Block as Treatments for Acute Myeloid Leukemia

降低hERG阻滞的IRAK1/4/泛FLT3激酶抑制剂可治疗急性髓系白血病

Hoyt, Scott B; Finocchio, Chris J; Croll, Elizabeth; Tawa, Gregory J; Zhang, Mingliang; Wang, Jiangong; Li, Huixi; Ma, Li; Li, Kaikai; Zhang, Xiaohu; Xu, Xin; Shah, Pranav; Fang, Yuhong; Bolanos, Lyndsey C; Gracia-Maldonado, Gabriel; Kolt, Amal; Robinson, Christina; Free, Jessica; Edmondson, Elijah F; Difilippantonio, Simone; Jones, LaQuita M; Culver-Cochran, Ashley E; Rosenbaum, Jan S; Starczynowski, Daniel T; Thomas, Craig J

Chemotherapy resistance in acute myeloid leukemia is mediated by A20 suppression of spontaneous necroptosis

急性髓系白血病的化疗耐药性是由 A20 抑制自发性坏死性凋亡介导的

Ashley E Culver-Cochran, Aishlin Hassan, Kathleen Hueneman, Kwangmin Choi, Averil Ma, Brett VanCauwenbergh, Eric O'Brien, Mark Wunderlich, John P Perentesis, Daniel T Starczynowski

Discovery of IRAK1/4/pan-FLT3 Kinase Inhibitors as Treatments for Acute Myeloid Leukemia

发现IRAK1/4/泛FLT3激酶抑制剂可作为急性髓系白血病的治疗方法

Hoyt, Scott B; Finocchio, Chris J; Croll, Elizabeth; Tawa, Gregory J; Li, Huixu; Ma, Li; Li, Kaikai; Liu, Li; Li, Ranran; Zhang, Xiaohu; Wilson, Kelli; Xu, Xin; Shah, Pranav; Williams, Jordan; Fang, Yuhong; Bolanos, Lyndsey C; Gracia-Maldonado, Gabriel; Kolt, Amal; Robinson, Christina; Free, Jessica; Edmondson, Elijah F; Difilippantonio, Simone; Jones, LaQuita M; Culver-Cochran, Ashley E; Rosenbaum, Jan S; Starczynowski, Daniel T; Thomas, Craig J

The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia

去泛素化酶 USP15 调节细胞氧化还原,是急性髓系白血病的治疗靶点

Madeline Niederkorn, Chiharu Ishikawa, Kathleen M Hueneman, James Bartram, Emily Stepanchick, Joshua R Bennett, Ashley E Culver-Cochran, Lyndsey C Bolanos, Emma Uible, Kwangmin Choi, Mark Wunderlich, John P Perentesis, Timothy M Chlon, Marie-Dominique Filippi, Daniel T Starczynowski

TNFAIP3 Plays a Role in Aging of the Hematopoietic System

TNFAIP3 在造血系统衰老中发挥作用

Molly A Smith, Ashley E Culver-Cochran, Emmalee R Adelman, Garrett W Rhyasen, Averil Ma, Maria E Figueroa, Daniel T Starczynowski

Chronic innate immune signaling results in ubiquitination of splicing machinery

慢性先天免疫信号传导会导致剪接机制的泛素化。

Culver-Cochran, Ashley E; Starczynowski, Daniel T

Characterization of a SILAC method for proteomic analysis of primary rat microglia

对用于大鼠原代小胶质细胞蛋白质组学分析的SILAC方法进行表征

Zhang, Ping; Culver-Cochran, Ashley E; Stevens, Stanley M Jr; Liu, Bin

Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics

基于细胞培养中氨基酸稳定同位素标记(SILAC)蛋白质组学的新型分子机制揭示了小胶质细胞经典和替代激活状态的机制

Bell-Temin, Harris; Culver-Cochran, Ashley E; Chaput, Dale; Carlson, Christina M; Kuehl, Melanie; Burkhardt, Brant R; Bickford, Paula C; Liu, Bin; Stevens, Stanley M Jr

Loss of WSTF results in spontaneous fluctuations of heterochromatin formation and resolution, combined with substantial changes to gene expression

WSTF 的缺失会导致异染色质形成和分解的自发波动,并伴随基因表达的重大变化

Ashley E Culver-Cochran, Brian P Chadwick