Targeting gp100 and TRP-2 with a DNA vaccine: Incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical outcome in a phase I/II trial
利用DNA疫苗靶向gp100和TRP-2:将T细胞表位与人IgG1抗体结合,可诱导强效的T细胞反应,并在I/II期临床试验中显示出良好的临床疗效。
期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2018.1433516
Patel, Poulam M; Ottensmeier, Christian H; Mulatero, Clive; Lorigan, Paul; Plummer, Ruth; Pandha, Hardev; Elsheikh, Somaia; Hadjimichael, Efthymios; Villasanti, Naty; Adams, Sally E; Cunnell, Michelle; Metheringham, Rachael L; Brentville, Victoria A; Machado, Lee; Daniels, Ian; Gijon, Mohamed; Hannaman, Drew; Durrant, Lindy G