日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways.

STING激活通过炎症细胞死亡途径诱导脑膜瘤细胞毒性和免疫反应。

Youngblood Mark W, Tripathi Shashwat, Najem Hinda, Congivaram Harrshavasan, Gomez Mateo, Sears Thomas K, Hurley Lisa, Billingham Leah K, Silvers Caylee, Wang Wenxia, Tiek Deanna, Sadagopan Nishanth, Chaliparambil Rahul, Pu Qianyi, Wai Ching Man, Choudhury Abrar, Steffens Alicia, McCortney Kathleen, Vazquez Cervantes Gustavo Ignacio, Oyon Daniel, Fernandez Luis, Selner Ashley, Fares Jawad, Hagan Matthew, Joy Trybula S, Yeung Jacky, Peyre Matthieu, Kalamarides Michel, Zhang Peng, Stegh Alexander H, Ashley David M, Horbinski Craig M, Ahrendsen Jared T, Jamshidi Pouya, Brat Daniel J, Lukas Rimas V, Stupp Roger, Lesniak Maciej S, Sonabend Adam M, Dunn Gavin P, Chandler James P, Tate Matthew C, Magill Stephen T, Miska Jason, Curran Michael A, Raleigh David R, Heimberger Amy B

STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma model

STING诱导的血脑屏障开放联合放射疗法可增强高级别胶质瘤模型中的抗肿瘤反应。

Tripathi, Shashwat; Najem, Hinda; Hurley, Lisa; Du, Ruochen; Dmello, Crismita; Ali, Heba; McCortney, Kathleen; Habashy, Karl J; Zhang, Peng; Horbinski, Craig M; Leoni, Lara; Avery, Ryan J; Lukas, Rimas V; Sita, Timothy L; Raleigh, David R; Sachdev, Sean; Stupp, Roger; Lesniak, Maciej S; Ashley, David M; Procissi, Daniele; Curran, Michael A; Balyasnikova, Irina; Heimberger, Amy B

Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade.

效应调节性 T 细胞的耗竭与诱导双重免疫检查点阻断的主要反应相关

Jiang Xianli, Rudqvist Nils-Petter, Jiang Bo, Ye Shengbin, He Shan, Liang Qingnan, Dou Jinzhuang, Williams Michelle D, Dunn Joe Dan, Johnson Jason M, Akagi Keiko, Xiao Weihong, Liang Shaoheng, Elayavalli Satvik, Sun Baohua, Parra Edwin R, Ferrarotto Renata, Garden Adam S, Fuller Clifton David, Reddy Jay, Gross Neil D, Lango Miriam N, Leung Cheuk Hong, Liu Suyu, Liu Diane D, Li Meng, Lee J Jack, Curran Michael A, Phan Jack, Chen Ken, Gillison Maura L

Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?

调节胶质母细胞瘤浸润髓系细胞上的免疫检查点是否是一种可行的治疗策略?

Du, Ruochen; Zhang, Jianzhong; Lukas, Rimas V; Tripathi, Shashwat; Ahrendsen, Jared T; Curran, Michael A; Dmello, Crismita; Zhang, Peng; Stupp, Roger; Rao, Ganesh; Heimberger, Amy B

The influence of the microbiome on radiotherapy and DNA damage responses

微生物组对放射治疗和DNA损伤反应的影响

Sheikh, Aadil; Curran, Michael A

Lefitolimod in Combination with Ipilimumab in Patients with Advanced Solid Tumors: A Phase I Trial

来非托利莫德联合伊匹木单抗治疗晚期实体瘤患者:一项 I 期试验

Nardo, Mirella; Gouda, Mohamed A; Reilley, Matthew J; Biter, Amadeo B; Lim, Joann; Bean, Stacie A; Nguyen, Ly M; Bhosale, Priya R; Ager, Casey R; Couillault, Coline A; Piha-Paul, Sarina A; Fu, Siqing; Tsimberidou, Apostolia M; Yap, Timothy A; Naing, Aung; Rodon, Jordi; Subbiah, Vivek; Karp, Daniel D; Curran, Michael A; Hong, David S

Tissue and Imaging Biomarkers of Response to Neoadjuvant Nivolumab or Nivolumab plus Ipilimumab in Patients with Resectable Hepatocellular Carcinoma.

可切除肝细胞癌患者接受新辅助纳武利尤单抗或纳武利尤单抗联合伊匹木单抗治疗的组织和影像生物标志物反应

LaPelusa Michael, Chamseddine Shadi, Tran Cao Hop Sanderson, Xiao Lianchun, Hasanov Elshad, Bhosale Priya, Amin Hesham M, Mohamed Yehia I, Gok Yavuz Betul, Sakr Yara, Xu Li, Hu Ian, Lee Sunyoung S, Sakamuri Divya, Jindal Sonali, Nguyen Van, Curran Michael A, Sun Ryan, Rashid Asif, Duda Dan Gabriel, Sharma Padmanee, Qayyum Aliya, Kaseb Ahmed Omar

Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

依沃福酰胺用于治疗人乳头瘤病毒阴性的头颈部鳞状细胞癌

Jamieson, Stephen Mf; Tsai, Peter; Kondratyev, Maria K; Budhani, Pratha; Liu, Arthur; Senzer, Neil N; Chiorean, E Gabriela; Jalal, Shadia I; Nemunaitis, John J; Kee, Dennis; Shome, Avik; Wong, Way W; Li, Dan; Poonawala-Lohani, Nooriyah; Kakadia, Purvi M; Knowlton, Nicholas S; Lynch, Courtney Rh; Hong, Cho R; Lee, Tet Woo; Grénman, Reidar A; Caporiccio, Laura; McKee, Trevor D; Zaidi, Mark; Butt, Sehrish; Macann, Andrew Mj; McIvor, Nicholas P; Chaplin, John M; Hicks, Kevin O; Bohlander, Stefan K; Wouters, Bradly G; Hart, Charles P; Print, Cristin G; Wilson, William R; Curran, Michael A; Hunter, Francis W

ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer

ATR介导的CD47和PD-L1上调限制了结直肠癌中放射治疗诱导的免疫启动和远隔效应。

Hsieh, Rodney Cheng-En; Krishnan, Sunil; Wu, Ren-Chin; Boda, Akash R; Liu, Arthur; Winkler, Michelle; Hsu, Wen-Hao; Lin, Steven Hsesheng; Hung, Mien-Chie; Chan, Li-Chuan; Bhanu, Krithikaa Rajkumar; Srinivasamani, Anupallavi; De Azevedo, Ricardo Alexandre; Chou, Yung-Chih; DePinho, Ronald A; Gubin, Matthew; Vilar, Eduardo; Chen, Chao Hsien; Slay, Ravaen; Jayaprakash, Priyamvada; Hegde, Shweta Mahendra; Hartley, Genevieve; Lea, Spencer T; Prasad, Rishika; Morrow, Brittany; Couillault, Coline Agnes; Steiner, Madeline; Wang, Chun-Chieh; Venkatesulu, Bhanu Prasad; Taniguchi, Cullen; Kim, Yon Son Betty; Chen, Junjie; Rudqvist, Nils-Petter; Curran, Michael A

ISA101 and nivolumab for HPV-16(+) cancer: updated clinical efficacy and immune correlates of response

ISA101 和纳武利尤单抗治疗 HPV-16(+) 癌症:最新临床疗效和免疫反应相关性

Sousa, Luana Guimaraes de; Rajapakshe, Kimal; Rodriguez Canales, Jaime; Chin, Renee L; Feng, Lei; Wang, Qi; Barrese, Tomas Z; Massarelli, Erminia; William, William; Johnson, Faye M; Ferrarotto, Renata; Wistuba, Ignacio; Coarfa, Cristian; Lee, Jack; Wang, Jing; Melief, Cornelis J M; Curran, Michael A; Glisson, Bonnie S