日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural Diversification of 14-Membered Macrolides by Chemoenzymatic Synthesis

通过化学酶法合成实现14元大环内酯的结构多样化

Curtis, Brian J; Boesger, Hannah A; Schmidt, Jennifer J; Adrover-Castellano, Maria L; Momin, Areeba N; Glasser, Carolyn A; Sherman, David H

Investigating Opioid Receptor Activity through Biocatalytic Halogenation and Oxidation of Mitragynine

通过生物催化卤化和氧化帽柱木碱研究阿片受体活性

Harris, Natalia R; Powell, Alexander J; Snodgrass, Harrison M; Amin, Sahar; Newmister, Sean A; Curtis, Brian J; Li, Danny; Husaini, Zehra A; Verhey-Henke, Linnea; Smith, Janet L; Pereira, Filipa; Lewis, Jared C; Traynor, John; Sherman, David H

Engineering a Biosynthetic Pathway to Produce (+)-Brevianamides A and B

构建生物合成途径以生产 (+)-布雷维酰胺 A 和 B

Sandoval Hurtado, Casandra P; Kelly, Samantha P; Shende, Vikram; Perez, Makayla; Curtis, Brian J; Newmister, Sean A; Ott, Kaleb; Pereira, Filipa; Sherman, David H

Directed Evolution of a Modular Polyketide Synthase Thioesterase for Generation of a Hybrid Macrocyclic Ring System

利用模块化聚酮合酶硫酯酶定向进化生成杂化大环体系

Adrover-Castellano, Maria L; Curtis, Brian J; Schmidt, Jennifer J; Boesger, Hannah A; Glasser, Carolyn A; Olukorede, Damilola E; Qu, Fengrui; Sherman, David H

Metabolic engineering and late-stage functionalization expand the chemical space of the antimalarial premarineosin A

代谢工程和后期功能化扩展了抗疟药普瑞马利尼奥辛A的化学空间。

McBride, Christina M; McCauley, Morgan; Harris, Natalia R; Amin, Sahar; Curtis, Brian J; Verhey-Henke, Linnea; Teklemichael, Awet A; Oliphant, Erin N; Dranchak, Patricia; Lev, Katherine L; Qu, Fengrui; Snodgrass, Harrison M; Lewis, Jared C; Inglese, James; Su, Xin-Zhuan; Pereira, Filipa; Sherman, David H

Host-microbe interactions rewire metabolism in a C. elegans model of leucine breakdown deficiency.

在秀丽隐杆线虫亮氨酸分解缺乏模型中,宿主-微生物相互作用重塑了代谢

Lee Yong-Uk, Fox Bennett W, Guo Rui, Curtis Brian J, Yu Jingfang, Kim Sookyung, Nanda Shivani, Baumann Victor, Yilmaz L Safak, Haynes Cole M, Schroeder Frank C, Walhout Albertha J M

Author Correction: Evolutionarily related host and microbial pathways regulate fat desaturation in C. elegans

作者更正:进化相关的宿主和微生物通路调控秀丽隐杆线虫中的脂肪去饱和作用

Fox, Bennett W; Helf, Maximilian J; Burkhardt, Russell N; Artyukhin, Alexander B; Curtis, Brian J; Palomino, Diana Fajardo; Schroeder, Allen F; Chaturbedi, Amaresh; Tauffenberger, Arnaud; Wrobel, Chester J J; Zhang, Ying K; Lee, Siu Sylvia; Schroeder, Frank C

N-to-S Acyl Transfer as an Enabling Strategy in Asymmetric and Chemoenzymatic Synthesis

N-S酰基转移作为不对称和化学酶法合成中的一种关键策略

Jo, Woonkee S; Curtis, Brian J; Rehan, Mohammad; Adrover-Castellano, Maria L; Sherman, David H; Healy, Alan R

Oligonucleotide Catabolism-Derived Gluconucleosides in Caenorhabditis elegans

秀丽隐杆线虫中寡核苷酸分解代谢衍生的葡糖核苷

Curtis, Brian J; Schwertfeger, Tyler J; Burkhardt, Russell N; Fox, Bennett W; Andrzejewski, Jude; Wrobel, Chester J J; Yu, Jingfang; Rodrigues, Pedro R; Tauffenberger, Arnaud; Schroeder, Frank C

Combinatorial Assembly of Modular Glucosides via Carboxylesterases Regulates C. elegans Starvation Survival

羧酸酯酶介导的模块化糖苷组合组装调控秀丽隐杆线虫的饥饿存活

Wrobel, Chester J J; Yu, Jingfang; Rodrigues, Pedro R; Ludewig, Andreas H; Curtis, Brian J; Cohen, Sarah M; Fox, Bennett W; O'Donnell, Michael P; Sternberg, Paul W; Schroeder, Frank C