日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Profiling Peripheral Blood with an Optimized, Multiplexed, Single-cell Multiome Approach Supports an Insulin-driven Asthma Subtype

利用优化的多重单细胞多组学方法对外周血进行分析,支持胰岛素驱动型哮喘亚型的观点。

Ding, Jiacheng; Kang, HyunJin; Spangenberg, Amber L; Liu, Yusha; Martinez, Fernando D; Carr, Tara F; Cusanovich, Darren A

Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors

基于细胞的高内涵方法鉴定出SARS-CoV-2中和作用的独特单克隆抗体和PI3K通路抑制剂

Cabel, Carly R; Guzman, Briana A; Alizadeh, Elaheh; Li, Shuaizhi; Holberg, Cameron; Wichaidit, Chonlarat; Cusanovich, Darren A; Paek, Andrew L; Thatcher, Gregory R J; Van Doorslaer, Koenraad; Nargi, Rachel S; Sutton, Rachel E; Suryadevara, Naveenchandra; Crowe, James E Jr; Carnahan, Robert H; Campos, Samuel K; Thorne, Curtis A

Optimization of a Cas12a-Driven Synthetic Gene Regulatory Network System.

Cas12a驱动的合成基因调控网络系统的优化

Kang HyunJin, Fitch John C, Varghese Reeba P, Thorne Curtis A, Cusanovich Darren A

Early, adjuvant-responsive epigenetic programs in B cells imprint subsequent plasma cell survival and the duration of humoral immunity.

B 细胞中早期对佐剂有反应的表观遗传程序会影响后续浆细胞的存活和体液免疫的持续时间

Ripperger Tyler J, D'Souza Lucas J, Read James F, Qi Wenjie, Cusanovich Darren A, Schultz-Cherry Stacey, Corcoran Lynn M, Bosco Anthony, Bhattacharya Deepta

txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility

txci-ATAC-seq:一种用于分析染色质可及性的大规模单细胞技术

Hao Zhang # ,Ryan M Mulqueen # ,Natalie Iannuzo ,Dominique O Farrera ,Francesca Polverino ,James J Galligan ,Julie G Ledford ,Andrew C Adey ,Darren A Cusanovich

Single-cell 'omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations

体外人主动脉内皮细胞和体外人动脉粥样硬化病变的单细胞组学图谱揭示了内皮细胞亚型的异质性和对激活扰动的反应

Maria L Adelus, Jiacheng Ding, Binh T Tran, Austin C Conklin, Anna K Golebiewski, Lindsey K Stolze, Michael B Whalen, Darren A Cusanovich, Casey E Romanoski

Single cell 'omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveals heterogeneity of endothelial subtype and response to activating perturbations

体外人主动脉内皮细胞和体外人动脉粥样硬化病变的单细胞组学图谱揭示了内皮细胞亚型的异质性和对激活扰动的反应

Maria L Adelus, Jiacheng Ding, Binh T Tran, Austin C Conklin, Anna K Golebiewski, Lindsey K Stolze, Michael B Whalen, Darren A Cusanovich, Casey E Romanoski

CC16 drives VLA-2-dependent SPLUNC1 expression

CC16 驱动 VLA-2 依赖的 SPLUNC1 表达

Natalie Iannuzo, Holly Welfley, Nicholas C Li, Michael D L Johnson, Joselyn Rojas-Quintero, Francesca Polverino, Stefano Guerra, Xingnan Li, Darren A Cusanovich, Paul R Langlais, Julie G Ledford

Single-Cell Profiling of Premature Neonate Airways Reveals a Continuum of Myeloid Differentiation

早产新生儿气道单细胞分析揭示髓系分化的连续过程

Welfley, Holly; Kylat, Ranjit; Zaghloul, Nahla; Halonen, Marilyn; Martinez, Fernando D; Ahmed, Mohamed; Cusanovich, Darren A

SGRN: A Cas12a-driven Synthetic Gene Regulatory Network System

SGRN:Cas12a 驱动的合成基因调控网络系统

HyunJin Kang, John C Fitch, Reeba P Varghese, Curtis A Thorne, Darren A Cusanovich