日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conditional knockout mouse model demonstrates that Copa expression is required for viability in development and adulthood.

条件性基因敲除小鼠模型表明,Copa 表达是发育和成年期生存所必需的

Gilson Timra, Astroski Jacob W, Qun Wang, Turner Matthew J, Androphy Elliot J, Custer Sara K

Interaction between alpha-COP and SMN ameliorates disease phenotype in a mouse model of spinal muscular atrophy.

α-COP 与 SMN 的相互作用可改善脊髓性肌萎缩症小鼠模型的疾病表型

Custer Sara K, Astroski Jacob W, Li Hong Xia, Androphy Elliot J

Identification of a resilient mouse facial motoneuron population following target disconnection by injury or disease

损伤或疾病导致靶点连接中断后,鉴定出具有恢复能力的小鼠面部运动神经元群

Setter, Deborah O; Haulcomb, Melissa M; Beahrs, Taylor; Meadows, Rena M; Schartz, Nicole D; Custer, Sara K; Sanders, Virginia M; Jones, Kathryn J

Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction

共济蛋白-7的蛋白水解切割促进SCA7视网膜变性和神经功能障碍

Guyenet, Stephan J; Mookerjee, Shona S; Lin, Amy; Custer, Sara K; Chen, Sylvia F; Sopher, Bryce L; La Spada, Albert R; Ellerby, Lisa M

α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth

α-COP与运动神经元存活蛋白SMN的结合是神经元突起生长所必需的。

Li, Hongxia; Custer, Sara K; Gilson, Timra; Hao, Le Thi; Beattie, Christine E; Androphy, Elliot J

Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy

脊髓性肌萎缩症细胞培养和动物模型中的自噬失调

Custer, Sara K; Androphy, Elliot J

Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy

SMN蛋白第2b外显子中的二赖氨酸基序介导其与COPI囊泡蛋白α-COP的结合,并在脊髓性肌萎缩症细胞培养模型中促进神经突生长。

Custer, Sara K; Todd, Adrian G; Singh, Natalia N; Androphy, Elliot J

TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.

TDP-43 在一种由 VCP/p97 突变引起的新型果蝇疾病模型中介导退化

Ritson Gillian P, Custer Sara K, Freibaum Brian D, Guinto Jake B, Geffel Dyanna, Moore Jennifer, Tang Waixing, Winton Matthew J, Neumann Manuela, Trojanowski John Q, Lee Virginia M-Y, Forman Mark S, Taylor J Paul