日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice

新型脂化咪唑喹啉TLR7/8佐剂可诱导流感特异性Th1免疫反应,并保护小鼠免受异源H3N2流感病毒攻击

Miller, Shannon M; Cybulski, Van; Whitacre, Margaret; Bess, Laura S; Livesay, Mark T; Walsh, Lois; Burkhart, David; Bazin, Hélène G; Evans, Jay T

Optimization of 8-oxoadenines with toll-like-receptor 7 and 8 activity

优化具有 Toll 样受体 7 和 8 活性的 8-氧代腺嘌呤。

Bazin, Hélène G; Bess, Laura S; Livesay, Mark T; Li, Yufeng; Cybulski, Van; Miller, Shannon M; Johnson, David A; Evans, Jay T

Co-encapsulation of synthetic lipidated TLR4 and TLR7/8 agonists in the liposomal bilayer results in a rapid, synergistic enhancement of vaccine-mediated humoral immunity.

将合成的脂化 TLR4 和 TLR7/8 激动剂共同封装在脂质体双层中,可快速协同增强疫苗介导的体液免疫

Short Kristopher K, Miller Shannon M, Walsh Lois, Cybulski Van, Bazin Hélène, Evans Jay T, Burkhart David

Synthetic Toll-like Receptors 7 and 8 Agonists: Structure-Activity Relationship in the Oxoadenine Series.

合成 Toll 样受体 7 和 8 激动剂:氧代腺嘌呤系列的结构-活性关系

Evans Jay T, Bess Laura S, Mwakwari Sandra C, Livesay Mark T, Li Yufeng, Cybulski Van, Johnson David A, Bazin Hélène G