Czeloth相关文献与解析，生知库 | 链接生命科学的每一步

Laurentino, Sandra; Cremers, Jann-Frederik; Horsthemke, Bernhard; Tüttelmann, Frank; Czeloth, Karen; Zitzmann, Michael; Pohl, Eva; Rahmann, Sven; Schröder, Christopher; Berres, Sven; Redmann, Klaus; Krallmann, Claudia; Schlatt, Stefan; Kliesch, Sabine; Gromoll, Jörg

细胞生物学

衰老

发表日期：2020

文献求助收藏

A randomized, single-blind, Phase I trial (INVICTAN-1) assessing the bioequivalence and safety of BI 695502, a bevacizumab biosimilar candidate, in healthy subjects

一项随机、单盲 I 期试验 (INVICTAN-1)，评估贝伐单抗生物仿制药候选药物 BI 695502 在健康受试者中的生物等效性和安全性

期刊:Expert Opinion on Investigational Drugs

影响因子:4.9

doi:10.1080/13543784.2017.1347635

Willem Hettema, Christopher Wynne, Benjamin Lang, Mario Altendorfer, Niklas Czeloth, Ragna Lohmann, Sandeep Athalye, Dorothee Schliephake

信号转导

发表日期：2017

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Bioequivalence, safety and immunogenicity of BI 695501, an adalimumab biosimilar candidate, compared with the reference biologic in a randomized, double-blind, active comparator phase I clinical study (VOLTAIRE®-PK) in healthy subjects

在健康受试者中进行的随机、双盲、活性对照 I 期临床研究 (VOLTAIRE®-PK) 中，阿达木单抗生物仿制药候选药物 BI 695501 与参考生物制剂的生物等效性、安全性和免疫原性进行了比较

期刊:Expert Opinion on Investigational Drugs

影响因子:4.9

doi:10.1080/13543784.2016.1255724

Christopher Wynne, Mario Altendorfer, Ivo Sonderegger, Lien Gheyle, Rod Ellis-Pegler, Susanne Buschke, Benjamin Lang, Deepak Assudani, Sandeep Athalye, Niklas Czeloth

免疫

发表日期：2016

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Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells

抗体诱导的 T 细胞 CD4 下调是由 CD64(+) 细胞位点特异性介导的

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/srep18308

Stephanie Vogel, Elena Grabski, Daniela Buschjäger, Frank Klawonn, Marius Döring, Junxi Wang, Erika Fletcher, Ingo Bechmann, Torsten Witte, Martin Durisin, Burkhart Schraven, Sara M Mangsbo, Kurt Schönfeld, Niklas Czeloth, Ulrich Kalinke

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

tregalizumab 结合的特定 CD4 表位通过独特的信号通路介导调节性 T 细胞的激活

期刊:Immunology and Cell Biology

影响因子:3.2

doi:10.1038/icb.2014.102

Bianca Helling, Martin König, Benjamin Dälken, Andre Engling, Wolfgang Krömer, Katharina Heim, Holger Wallmeier, Jürgen Haas, Brigitte Wildemann, Brigitte Fritz, Helmut Jonuleit, Jan Kubach, Theodor Dingermann, Heinfried H Radeke, Frank Osterroth, Christoph Uherek, Niklas Czeloth, Jörg Schüttrumpf

Intranodal interaction with dendritic cells dynamically regulates surface expression of the co-stimulatory receptor CD226 protein on murine T cells

与树突状细胞的节内相互作用动态调节小鼠 T 细胞上共刺激受体 CD226 蛋白的表面表达

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.M111.264697

Sebastian Seth, Quan Qiu, Simon Danisch, Michael K Maier, Asolina Braun, Inga Ravens, Niklas Czeloth, Rebecca Hyde, Oliver Dittrich-Breiholz, Reinhold Förster, Günter Bernhardt

A germ cell-specific ageing pattern in otherwise healthy men

在其他方面健康的男性中，生殖细胞特异性衰老模式

A randomized, single-blind, Phase I trial (INVICTAN-1) assessing the bioequivalence and safety of BI 695502, a bevacizumab biosimilar candidate, in healthy subjects

一项随机、单盲 I 期试验 (INVICTAN-1)，评估贝伐单抗生物仿制药候选药物 BI 695502 在健康受试者中的生物等效性和安全性

Bioequivalence, safety and immunogenicity of BI 695501, an adalimumab biosimilar candidate, compared with the reference biologic in a randomized, double-blind, active comparator phase I clinical study (VOLTAIRE®-PK) in healthy subjects

在健康受试者中进行的随机、双盲、活性对照 I 期临床研究 (VOLTAIRE®-PK) 中，阿达木单抗生物仿制药候选药物 BI 695501 与参考生物制剂的生物等效性、安全性和免疫原性进行了比较

Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells

抗体诱导的 T 细胞 CD4 下调是由 CD64(+) 细胞位点特异性介导的

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

tregalizumab 结合的特定 CD4 表位通过独特的信号通路介导调节性 T 细胞的激活

Intranodal interaction with dendritic cells dynamically regulates surface expression of the co-stimulatory receptor CD226 protein on murine T cells

与树突状细胞的节内相互作用动态调节小鼠 T 细胞上共刺激受体 CD226 蛋白的表面表达